/* CSS Reset and Base Styles */
* {
    margin: 0;
    padding: 0;
    box-sizing: border-box;
}

/* Skip Link for Accessibility */
.skip-link {
    position: absolute;
    top: -40px;
    left: 0;
    padding: 8px 16px;
    background: var(--primary-600);
    color: white;
    text-decoration: none;
    font-weight: 500;
    border-radius: 0 0 var(--radius) 0;
    z-index: 10000;
    transition: top 0.3s ease;
}

.skip-link:focus {
    top: 0;
    outline: 3px solid var(--primary-300);
    outline-offset: 2px;
}

/* Copy Button for Results */
.result-box-wrapper {
    position: relative;
}

.copy-btn {
    position: absolute;
    top: 8px;
    right: 8px;
    padding: 6px 10px;
    background: var(--gray-100);
    border: 1px solid var(--gray-300);
    border-radius: var(--radius-sm);
    cursor: pointer;
    font-size: 12px;
    color: var(--gray-600);
    transition: all 0.2s ease;
    display: flex;
    align-items: center;
    gap: 4px;
}

.copy-btn:hover {
    background: var(--gray-200);
    color: var(--gray-800);
}

.copy-btn.copied {
    background: var(--success);
    color: white;
    border-color: var(--success);
}

.copy-btn i {
    font-size: 11px;
}

/* ES Conversion Usage Guide */
.es-usage-hint {
    background: linear-gradient(135deg, var(--info) 0%, var(--accent-600) 100%);
    color: white;
    padding: 12px 16px;
    border-radius: var(--radius);
    margin-bottom: 16px;
    font-size: 14px;
}

.es-usage-hint strong {
    display: block;
    margin-bottom: 4px;
    font-size: 14px;
}

.es-usage-hint ul {
    margin: 8px 0 0 20px;
    font-size: 13px;
}

.es-usage-hint li {
    margin-bottom: 4px;
}

/* Required Field Indicator */
.required-indicator {
    color: var(--error);
    margin-left: 2px;
}

/* Input Validation Feedback */
.input-group input.invalid,
.input-group select.invalid {
    border-color: var(--error);
    box-shadow: 0 0 0 3px rgba(239, 68, 68, 0.15);
}

.input-group input.valid,
.input-group select.valid {
    border-color: var(--success);
}

.validation-message {
    color: var(--error);
    font-size: 12px;
    margin-top: 4px;
    display: none;
}

.validation-message.show {
    display: block;
}

/* CSS Custom Properties for Design System */
:root {
    /* Primary Color Palette - Teal/Cyan */
    --primary-50: #f0fdfa;
    --primary-100: #ccfbf1;
    --primary-200: #99f6e4;
    --primary-300: #5eead4;
    --primary-400: #2dd4bf;
    --primary-500: #14b8a6;
    --primary-600: #0d9488;
    --primary-700: #0f766e;
    --primary-800: #115e59;
    --primary-900: #134e4a;

    /* Secondary/Accent Colors - Blue */
    --accent-50: #eff6ff;
    --accent-100: #dbeafe;
    --accent-200: #bfdbfe;
    --accent-300: #93c5fd;
    --accent-400: #60a5fa;
    --accent-500: #3b82f6;
    --accent-600: #2563eb;
    --accent-700: #1d4ed8;
    --accent-800: #1e40af;
    --accent-900: #1e3a8a;

    /* Neutral Colors */
    --gray-50: #f9fafb;
    --gray-100: #f3f4f6;
    --gray-200: #e5e7eb;
    --gray-300: #d1d5db;
    --gray-400: #9ca3af;
    --gray-500: #6b7280;
    --gray-600: #4b5563;
    --gray-700: #374151;
    --gray-800: #1f2937;
    --gray-900: #111827;

    /* Semantic Colors */
    --success: #10b981;
    --warning: #f59e0b;
    --error: #ef4444;
    --info: #3b82f6;

    /* Typography */
    --font-sans: 'Inter', -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;
    --font-mono: 'JetBrains Mono', 'Fira Code', Consolas, monospace;

    /* Spacing Scale */
    --space-1: 0.25rem;
    --space-2: 0.5rem;
    --space-3: 0.75rem;
    --space-4: 1rem;
    --space-5: 1.25rem;
    --space-6: 1.5rem;
    --space-8: 2rem;
    --space-10: 2.5rem;
    --space-12: 3rem;
    --space-16: 4rem;
    --space-20: 5rem;

    /* Border Radius */
    --radius-sm: 0.375rem;
    --radius: 0.5rem;
    --radius-md: 0.75rem;
    --radius-lg: 1rem;
    --radius-xl: 1.5rem;
    --radius-2xl: 2rem;

    /* Shadows */
    --shadow-sm: 0 1px 2px 0 rgba(0, 0, 0, 0.05);
    --shadow: 0 1px 3px 0 rgba(0, 0, 0, 0.1), 0 1px 2px 0 rgba(0, 0, 0, 0.06);
    --shadow-md: 0 4px 6px -1px rgba(0, 0, 0, 0.1), 0 2px 4px -1px rgba(0, 0, 0, 0.06);
    --shadow-lg: 0 10px 15px -3px rgba(0, 0, 0, 0.1), 0 4px 6px -2px rgba(0, 0, 0, 0.05);
    --shadow-xl: 0 20px 25px -5px rgba(0, 0, 0, 0.1), 0 10px 10px -5px rgba(0, 0, 0, 0.04);
}

body {
    font-family: var(--font-sans);
    line-height: 1.6;
    color: var(--gray-800);
    background: linear-gradient(135deg, var(--gray-50) 0%, var(--primary-50) 100%);
    -webkit-font-smoothing: antialiased;
    -moz-osx-font-smoothing: grayscale;
}

.container {
    max-width: 1400px;
    margin: 0 auto;
    padding: 0 20px;
}

/* Header Styles */
.header {
    background: linear-gradient(135deg, var(--primary-600) 0%, var(--accent-700) 100%);
    color: white;
    padding: var(--space-12) 0;
    box-shadow: var(--shadow-xl);
    position: relative;
    overflow: hidden;
}

.header::before {
    content: '';
    position: absolute;
    top: 0;
    left: 0;
    right: 0;
    bottom: 0;
    background: url("data:image/svg+xml,%3csvg xmlns='http://www.w3.org/2000/svg' viewBox='0 0 32 32' width='32' height='32' fill='none' stroke='%23ffffff10'%3e%3cpath d='m0 2 30 30m2-30L2 32'/%3e%3c/svg%3e");
    opacity: 0.5;
}

.header .container {
    position: relative;
    z-index: 1;
}

.header h1 {
    font-size: clamp(2rem, 5vw, 3rem);
    font-weight: 800;
    margin-bottom: var(--space-3);
    text-align: center;
    letter-spacing: -0.025em;
    text-shadow: 0 2px 4px rgba(0, 0, 0, 0.1);
}

.header h1 i {
    margin-right: var(--space-3);
    color: var(--primary-200);
    filter: drop-shadow(0 2px 4px rgba(0, 0, 0, 0.1));
}

.subtitle {
    text-align: center;
    font-size: clamp(1rem, 3vw, 1.25rem);
    color: white;
    opacity: 0.95;
    margin-bottom: var(--space-6);
    font-weight: 400;
    letter-spacing: 0.025em;
}

.version-info {
    text-align: center;
    font-size: 0.875rem;
    font-weight: 500;
    color: white;
    background: rgba(255, 255, 255, 0.15);
    backdrop-filter: blur(10px);
    border: 1px solid rgba(255, 255, 255, 0.2);
    display: inline-block;
    padding: var(--space-2) var(--space-4);
    border-radius: var(--radius-xl);
    margin: 0 auto;
    display: block;
    width: fit-content;
    transition: all 0.3s ease;
}

.version-info:hover {
    background: rgba(255, 255, 255, 0.2);
    transform: translateY(-1px);
}

/* Navigation Tabs */
.nav-tabs {
    background: white;
    border-bottom: 1px solid var(--gray-200);
    position: sticky;
    top: 0;
    z-index: 100;
    box-shadow: var(--shadow-sm);
    backdrop-filter: blur(8px);
}

.nav-tabs .container {
    display: flex;
    overflow-x: auto;
    gap: 0;
    scrollbar-width: none;
    -ms-overflow-style: none;
}

.nav-tabs .container::-webkit-scrollbar {
    display: none;
}

.tab-btn {
    background: none;
    border: none;
    padding: var(--space-4) var(--space-6);
    cursor: pointer;
    font-size: 0.9rem;
    font-weight: 600;
    color: var(--gray-500);
    border-bottom: 2px solid transparent;
    transition: all 0.3s cubic-bezier(0.4, 0, 0.2, 1);
    white-space: nowrap;
    display: flex;
    align-items: center;
    gap: var(--space-2);
    position: relative;
    letter-spacing: 0.025em;
}

.tab-btn::before {
    content: '';
    position: absolute;
    bottom: 0;
    left: 50%;
    transform: translateX(-50%) scaleX(0);
    width: 100%;
    height: 2px;
    background: linear-gradient(90deg, var(--primary-500), var(--accent-500));
    border-radius: 1px;
    transition: transform 0.3s cubic-bezier(0.4, 0, 0.2, 1);
}

.tab-btn:hover {
    color: var(--gray-700);
    background: linear-gradient(135deg, var(--primary-50), var(--accent-50));
}

.tab-btn.active {
    color: var(--primary-600);
    background: linear-gradient(135deg, var(--primary-50), var(--accent-50));
}

.tab-btn.active::before {
    transform: translateX(-50%) scaleX(1);
}

.tab-btn i {
    font-size: 1rem;
    transition: transform 0.2s ease;
}

.tab-btn:hover i {
    transform: scale(1.1);
}

/* Disabled Tab */
.tab-btn.tab-disabled {
    opacity: 0.5;
    cursor: not-allowed;
    pointer-events: none;
    position: relative;
}

.tab-btn.tab-disabled:hover {
    background: transparent;
    transform: none;
}

.badge-dev {
    display: inline-block;
    background: linear-gradient(135deg, #f59e0b, #d97706);
    color: white;
    font-size: 0.65rem;
    padding: 2px 6px;
    border-radius: 10px;
    margin-left: 6px;
    font-weight: 600;
    text-transform: uppercase;
    letter-spacing: 0.5px;
    vertical-align: middle;
}

/* Main Content */
.main-content {
    padding: var(--space-8) 0;
    min-height: calc(100vh - 200px);
}

.tab-content {
    display: none;
    animation: fadeIn 0.4s ease-out;
}

.tab-content.active {
    display: block;
}

@keyframes fadeIn {
    from {
        opacity: 0;
        transform: translateY(10px);
    }
    to {
        opacity: 1;
        transform: translateY(0);
    }
}

/* Typography Scale */
h1 {
    font-size: clamp(2rem, 5vw, 3rem);
    font-weight: 800;
    line-height: 1.2;
    letter-spacing: -0.025em;
}

h2 {
    font-size: clamp(1.5rem, 4vw, 2.25rem);
    font-weight: 700;
    line-height: 1.3;
    letter-spacing: -0.025em;
}

h3 {
    font-size: clamp(1.25rem, 3vw, 1.75rem);
    font-weight: 600;
    line-height: 1.4;
}

h4 {
    font-size: clamp(1.1rem, 2.5vw, 1.375rem);
    font-weight: 600;
    line-height: 1.4;
}

p {
    font-size: 1rem;
    line-height: 1.7;
    color: var(--gray-600);
}

/* Module Headers */
.module-header {
    text-align: center;
    margin-bottom: var(--space-8);
    padding: var(--space-10) var(--space-8);
    background: linear-gradient(135deg, white 0%, var(--primary-50) 100%);
    border-radius: var(--radius-xl);
    box-shadow: var(--shadow-lg);
    border: 1px solid var(--primary-100);
    position: relative;
    overflow: hidden;
}

.module-header::before {
    content: '';
    position: absolute;
    top: -50%;
    left: -50%;
    width: 200%;
    height: 200%;
    background: radial-gradient(circle, var(--primary-100) 0%, transparent 70%);
    opacity: 0.3;
    animation: float 6s ease-in-out infinite;
}

@keyframes float {
    0%, 100% {
        transform: translate(-50%, -50%) rotate(0deg);
    }
    50% {
        transform: translate(-50%, -50%) rotate(180deg);
    }
}

.module-header h2 {
    color: var(--gray-800);
    margin-bottom: var(--space-3);
    position: relative;
    z-index: 1;
    text-shadow: 0 1px 2px rgba(0, 0, 0, 0.05);
}

.module-header p {
    font-size: 1.125rem;
    color: var(--gray-600);
    max-width: 600px;
    margin: 0 auto;
    position: relative;
    z-index: 1;
}

/* Calculator Grid */
.calculator-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(400px, 1fr));
    gap: 2rem;
    margin-top: 2rem;
}

/* Card System */
.card {
    background: white;
    border-radius: var(--radius-lg);
    padding: var(--space-6);
    box-shadow: var(--shadow-md);
    border: 1px solid var(--gray-100);
    transition: all 0.3s cubic-bezier(0.4, 0, 0.2, 1);
    position: relative;
    overflow: hidden;
}

.card::before {
    content: '';
    position: absolute;
    top: 0;
    left: 0;
    right: 0;
    height: 4px;
    background: linear-gradient(90deg, var(--primary-500), var(--accent-500));
    opacity: 0;
    transition: opacity 0.3s ease;
}

.card:hover {
    transform: translateY(-4px);
    box-shadow: var(--shadow-xl);
    border-color: var(--primary-100);
}

.card:hover::before {
    opacity: 1;
}

/* Calculator Cards */
.calculator-card {
    background: linear-gradient(145deg, white 0%, var(--gray-50) 100%);
    border-radius: var(--radius-xl);
    padding: var(--space-8);
    box-shadow: var(--shadow-lg);
    border: 1px solid var(--gray-100);
    transition: all 0.4s cubic-bezier(0.4, 0, 0.2, 1);
    position: relative;
    backdrop-filter: blur(10px);
}

.calculator-card::before {
    content: '';
    position: absolute;
    top: 0;
    left: 0;
    right: 0;
    height: 3px;
    background: linear-gradient(90deg, var(--primary-500), var(--accent-500));
    border-radius: var(--radius-xl) var(--radius-xl) 0 0;
    opacity: 0;
    transition: all 0.3s ease;
}

.calculator-card:hover {
    transform: translateY(-6px) scale(1.02);
    box-shadow: var(--shadow-xl);
    border-color: var(--primary-200);
    background: linear-gradient(145deg, white 0%, var(--primary-50) 100%);
}

.calculator-card:hover::before {
    opacity: 1;
    height: 4px;
}

.calculator-card h3 {
    color: var(--gray-800);
    margin-bottom: var(--space-6);
    font-size: 1.25rem;
    font-weight: 700;
    display: flex;
    align-items: center;
    gap: var(--space-3);
    position: relative;
    z-index: 1;
}

.calculator-card h3 i {
    color: var(--primary-600);
    font-size: 1.125rem;
    padding: var(--space-2);
    background: var(--primary-100);
    border-radius: var(--radius);
    transition: all 0.3s ease;
}

.calculator-card:hover h3 i {
    background: var(--primary-200);
    transform: scale(1.1);
}

/* Form Elements */
.input-group {
    margin-bottom: var(--space-5);
    position: relative;
}

.input-row {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(140px, 1fr));
    gap: var(--space-4);
    margin-bottom: var(--space-5);
}

.input-group label {
    display: block;
    margin-bottom: var(--space-2);
    font-weight: 600;
    color: var(--gray-700);
    font-size: 0.875rem;
    letter-spacing: 0.025em;
    cursor: pointer;
}

.input-group input,
.input-group select {
    width: 100%;
    padding: var(--space-3) var(--space-4);
    border: 2px solid var(--gray-200);
    border-radius: var(--radius);
    font-size: 1rem;
    font-family: var(--font-sans);
    background: white;
    transition: all 0.3s cubic-bezier(0.4, 0, 0.2, 1);
    box-shadow: var(--shadow-sm);
}

.input-group input:focus,
.input-group select:focus {
    outline: none;
    border-color: var(--primary-500);
    box-shadow: 0 0 0 3px var(--primary-100), var(--shadow);
    transform: translateY(-1px);
}

.input-group input:invalid {
    border-color: var(--error);
    box-shadow: 0 0 0 3px rgba(239, 68, 68, 0.1);
}

.input-group input[type="checkbox"] {
    width: 1.25rem;
    height: 1.25rem;
    margin-right: var(--space-2);
    accent-color: var(--primary-500);
    border-radius: var(--radius-sm);
    cursor: pointer;
}

.input-group input[type="checkbox"]:focus-visible {
    outline: 2px solid var(--primary-500);
    outline-offset: 2px;
}

/* Mobile touch targets - 44px minimum */
@media (max-width: 768px) {
    .input-group input[type="checkbox"] {
        width: 1.5rem;
        height: 1.5rem;
        min-width: 44px;
        min-height: 44px;
    }
}

.input-group input[type="number"]::-webkit-outer-spin-button,
.input-group input[type="number"]::-webkit-inner-spin-button {
    -webkit-appearance: none;
    margin: 0;
}

.input-group input[type="number"] {
    -moz-appearance: textfield;
}

/* Button System */
.btn {
    display: inline-flex;
    align-items: center;
    justify-content: center;
    gap: var(--space-2);
    padding: var(--space-3) var(--space-6);
    border: none;
    border-radius: var(--radius);
    font-family: var(--font-sans);
    font-size: 0.875rem;
    font-weight: 600;
    letter-spacing: 0.025em;
    cursor: pointer;
    transition: all 0.3s cubic-bezier(0.4, 0, 0.2, 1);
    position: relative;
    overflow: hidden;
    text-decoration: none;
    user-select: none;
    outline: none;
}

.btn::before {
    content: '';
    position: absolute;
    top: 50%;
    left: 50%;
    width: 0;
    height: 0;
    background: rgba(255, 255, 255, 0.2);
    border-radius: 50%;
    transform: translate(-50%, -50%);
    transition: width 0.6s, height 0.6s;
}

.btn:active::before {
    width: 300px;
    height: 300px;
}

/* Primary Button */
.calc-btn, .upload-btn, .template-btn, .download-btn,
.btn-primary {
    background: linear-gradient(135deg, var(--primary-600) 0%, var(--accent-600) 100%);
    color: white;
    box-shadow: var(--shadow);
    width: 100%;
    margin-bottom: var(--space-4);
    padding: var(--space-4) var(--space-6);
}

.calc-btn:hover, .upload-btn:hover, .template-btn:hover, .download-btn:hover,
.btn-primary:hover {
    transform: translateY(-2px);
    box-shadow: var(--shadow-lg);
    background: linear-gradient(135deg, var(--primary-700) 0%, var(--accent-700) 100%);
}

.calc-btn:active, .upload-btn:active, .template-btn:active, .download-btn:active,
.btn-primary:active {
    transform: translateY(0);
    box-shadow: var(--shadow);
}

/* Secondary Button */
.formula-btn,
.btn-secondary {
    background: white;
    color: var(--gray-700);
    border: 2px solid var(--gray-200);
    box-shadow: var(--shadow-sm);
    width: 100%;
}

.formula-btn:hover,
.btn-secondary:hover {
    background: var(--gray-50);
    border-color: var(--gray-300);
    color: var(--gray-800);
    transform: translateY(-1px);
    box-shadow: var(--shadow);
}

/* Outline Button */
.btn-outline {
    background: transparent;
    color: var(--primary-600);
    border: 2px solid var(--primary-200);
}

.btn-outline:hover {
    background: var(--primary-50);
    border-color: var(--primary-300);
    color: var(--primary-700);
}

/* Ghost Button */
.btn-ghost {
    background: transparent;
    color: var(--gray-600);
    border: 2px solid transparent;
}

.btn-ghost:hover {
    background: var(--gray-100);
    color: var(--gray-800);
}

/* Button Sizes */
.btn-sm {
    padding: var(--space-2) var(--space-4);
    font-size: 0.75rem;
}

.btn-lg {
    padding: var(--space-4) var(--space-8);
    font-size: 1rem;
}

/* Disabled State */
.btn:disabled {
    opacity: 0.5;
    cursor: not-allowed;
    transform: none !important;
    box-shadow: var(--shadow-sm) !important;
}

/* Result System */
.result-box {
    background: linear-gradient(135deg, var(--gray-50) 0%, white 100%);
    border: 2px solid var(--gray-200);
    border-radius: var(--radius-lg);
    padding: var(--space-6);
    margin: var(--space-5) 0;
    min-height: 80px;
    font-family: var(--font-mono);
    font-size: 0.875rem;
    white-space: pre-wrap;
    color: var(--gray-600);
    transition: all 0.3s cubic-bezier(0.4, 0, 0.2, 1);
    position: relative;
    overflow: hidden;
    box-shadow: var(--shadow-sm);
    /* 預設隱藏，有結果時才顯示 */
    display: none;
}

.result-box.has-result,
.result-box.has-error,
.result-box.loading {
    display: block;
}

.result-box::before {
    content: '';
    position: absolute;
    top: 0;
    left: 0;
    right: 0;
    height: 3px;
    background: var(--gray-300);
    transition: all 0.3s ease;
}

.result-box.has-result {
    background: linear-gradient(135deg, #ecfdf5 0%, #f0fdf4 100%);
    border-color: var(--success);
    color: #065f46;
    box-shadow: var(--shadow-md);
    transform: translateY(-2px);
}

.result-box.has-result::before {
    background: linear-gradient(90deg, var(--success), #22c55e);
}

.result-box.has-error {
    background: linear-gradient(135deg, #fef2f2 0%, #fefefe 100%);
    border-color: var(--error);
    color: #991b1b;
    box-shadow: var(--shadow-md);
    transform: translateY(-2px);
}

.result-box.has-error::before {
    background: linear-gradient(90deg, var(--error), #f87171);
}

.result-box.loading {
    background: linear-gradient(135deg, var(--primary-50) 0%, var(--accent-50) 100%);
    border-color: var(--primary-300);
    color: var(--primary-700);
    display: flex;
    align-items: center;
    justify-content: center;
    gap: 0.5rem;
}

.result-box.loading::before {
    background: linear-gradient(90deg, var(--primary-500), var(--accent-500));
    animation: shimmer 2s infinite;
}

.result-box.loading::after {
    content: "計算中...";
    font-weight: 500;
}

@keyframes shimmer {
    0% {
        transform: translateX(-100%);
    }
    100% {
        transform: translateX(100%);
    }
}

/* Back to Top Button */
.back-to-top {
    position: fixed;
    bottom: 2rem;
    right: 2rem;
    width: 48px;
    height: 48px;
    background: var(--primary-600);
    color: white;
    border: none;
    border-radius: 50%;
    cursor: pointer;
    display: flex;
    align-items: center;
    justify-content: center;
    font-size: 1.25rem;
    box-shadow: var(--shadow-lg);
    opacity: 0;
    visibility: hidden;
    transform: translateY(20px);
    transition: all 0.3s ease;
    z-index: 1000;
}

.back-to-top.visible {
    opacity: 1;
    visibility: visible;
    transform: translateY(0);
}

.back-to-top:hover {
    background: var(--primary-700);
    transform: translateY(-3px);
    box-shadow: var(--shadow-xl);
}

.back-to-top:active {
    transform: translateY(0);
}

@media (max-width: 768px) {
    .back-to-top {
        bottom: 1rem;
        right: 1rem;
        width: 44px;
        height: 44px;
    }
}

/* Copy Button */
.copy-btn {
    position: absolute;
    top: 0.5rem;
    right: 0.5rem;
    padding: 0.25rem 0.5rem;
    background: var(--gray-100);
    border: 1px solid var(--gray-300);
    border-radius: var(--radius-sm);
    font-size: 0.75rem;
    color: var(--gray-600);
    cursor: pointer;
    opacity: 0;
    transition: all 0.2s ease;
}

.result-box:hover .copy-btn {
    opacity: 1;
}

.copy-btn:hover {
    background: var(--primary-50);
    border-color: var(--primary-300);
    color: var(--primary-600);
}

.copy-btn.copied {
    background: var(--success);
    border-color: var(--success);
    color: white;
}

/* Enhanced Animations */
@keyframes slideInUp {
    from {
        opacity: 0;
        transform: translateY(30px);
    }
    to {
        opacity: 1;
        transform: translateY(0);
    }
}

@keyframes slideInLeft {
    from {
        opacity: 0;
        transform: translateX(-30px);
    }
    to {
        opacity: 1;
        transform: translateX(0);
    }
}

@keyframes pulse {
    0%, 100% {
        opacity: 1;
    }
    50% {
        opacity: 0.7;
    }
}

@keyframes bounce {
    0%, 20%, 53%, 80%, 100% {
        transform: translate3d(0, 0, 0);
    }
    40%, 43% {
        transform: translate3d(0, -8px, 0);
    }
    70% {
        transform: translate3d(0, -4px, 0);
    }
    90% {
        transform: translate3d(0, -2px, 0);
    }
}

/* Loading States */
.loading {
    position: relative;
}

.loading::after {
    content: '';
    position: absolute;
    top: 50%;
    left: 50%;
    width: 20px;
    height: 20px;
    margin: -10px 0 0 -10px;
    border: 2px solid var(--primary-200);
    border-top: 2px solid var(--primary-600);
    border-radius: 50%;
    animation: spin 1s linear infinite;
}

@keyframes spin {
    0% {
        transform: rotate(0deg);
    }
    100% {
        transform: rotate(360deg);
    }
}

/* Micro-interactions */
.interactive {
    transition: all 0.2s ease;
}

.interactive:hover {
    cursor: pointer;
}

.interactive:active {
    transform: scale(0.98);
}

/* Stagger Animation for Lists */
.stagger-item {
    animation: slideInUp 0.4s ease-out;
    animation-fill-mode: both;
}

.stagger-item:nth-child(1) { animation-delay: 0.1s; }
.stagger-item:nth-child(2) { animation-delay: 0.2s; }
.stagger-item:nth-child(3) { animation-delay: 0.3s; }
.stagger-item:nth-child(4) { animation-delay: 0.4s; }
.stagger-item:nth-child(5) { animation-delay: 0.5s; }
.stagger-item:nth-child(6) { animation-delay: 0.6s; }

/* Smooth Scrolling */
html {
    scroll-behavior: smooth;
}

/* Focus Visible for Better Accessibility */
.tab-btn:focus-visible,
.btn:focus-visible,
.input-group input:focus-visible,
.input-group select:focus-visible {
    outline: 2px solid var(--primary-500);
    outline-offset: 2px;
}

/* Enhanced Responsive Design */
/* Large screens */
@media (min-width: 1200px) {
    .container {
        max-width: 1400px;
        padding: 0 var(--space-8);
    }
    
    .calculator-grid {
        grid-template-columns: repeat(3, 1fr);
        gap: var(--space-8);
    }
    
    .module-header {
        padding: var(--space-12) var(--space-10);
    }
}

/* Medium screens */
@media (max-width: 1024px) {
    .calculator-grid {
        grid-template-columns: repeat(2, 1fr);
        gap: var(--space-6);
    }
    
    .nav-tabs .container {
        padding: 0 var(--space-4);
    }
    
    .input-row {
        grid-template-columns: 1fr;
        gap: var(--space-3);
    }
}

/* Tablet screens */
@media (max-width: 768px) {
    .container {
        padding: 0 var(--space-4);
    }
    
    .header {
        padding: var(--space-8) 0;
    }
    
    .nav-tabs {
        position: relative;
        overflow-x: auto;
    }
    
    .nav-tabs .container {
        justify-content: flex-start;
        min-width: max-content;
        padding: 0 var(--space-4);
    }
    
    .tab-btn {
        min-width: max-content;
        padding: var(--space-3) var(--space-4);
        font-size: 0.8rem;
    }
    
    .calculator-grid {
        grid-template-columns: 1fr;
        gap: var(--space-4);
    }
    
    .calculator-card {
        padding: var(--space-6);
    }
    
    .module-header {
        padding: var(--space-6) var(--space-4);
        margin-bottom: var(--space-6);
    }
    
    .main-content {
        padding: var(--space-6) 0;
    }
    
    /* Stack form elements on mobile */
    .input-row {
        grid-template-columns: 1fr;
    }
    
    /* Improve touch targets */
    .btn,
    .calc-btn,
    .upload-btn,
    .template-btn,
    .download-btn {
        min-height: 48px;
        font-size: 0.9rem;
    }
    
    .input-group input,
    .input-group select {
        min-height: 48px;
        font-size: 16px; /* Prevent zoom on iOS */
    }
}

/* Small mobile screens */
@media (max-width: 480px) {
    .container {
        padding: 0 var(--space-3);
    }
    
    .header h1 {
        font-size: 1.75rem;
    }
    
    .subtitle {
        font-size: 1rem;
    }
    
    .calculator-card {
        padding: var(--space-4);
        margin-bottom: var(--space-4);
    }
    
    .module-header {
        padding: var(--space-4);
        text-align: left;
    }
    
    .module-header h2 {
        font-size: 1.5rem;
    }
    
    .tab-btn {
        padding: var(--space-3);
        font-size: 0.75rem;
    }
    
    .tab-btn i {
        display: none; /* Hide icons on very small screens */
    }
    
    .result-box {
        font-size: 0.8rem;
        padding: var(--space-4);
    }
}

/* High DPI screens */
@media (-webkit-min-device-pixel-ratio: 2), (min-resolution: 192dpi) {
    .header h1,
    .module-header h2 {
        -webkit-font-smoothing: antialiased;
        -moz-osx-font-smoothing: grayscale;
    }
}

/* Dark mode support */
@media (prefers-color-scheme: dark) {
    :root {
        --gray-50: #111827;
        --gray-100: #1f2937;
        --gray-200: #374151;
        --gray-300: #4b5563;
        --gray-600: #d1d5db;
        --gray-700: #e5e7eb;
        --gray-800: #f9fafb;
        --gray-900: #ffffff;

        /* Adjusted primary colors for dark mode contrast */
        --primary-50: #134e4a;
        --primary-100: #115e59;
        --primary-200: #0f766e;
        --primary-300: #0d9488;
        --primary-400: #14b8a6;
        --primary-500: #2dd4bf;
        --primary-600: #5eead4;
        --primary-700: #99f6e4;

        /* Adjusted accent colors for dark mode */
        --accent-50: #1e3a8a;
        --accent-100: #1e40af;
        --accent-200: #1d4ed8;
        --accent-300: #2563eb;
        --accent-400: #3b82f6;
        --accent-500: #60a5fa;
    }

    body {
        background: linear-gradient(135deg, var(--gray-100) 0%, var(--gray-200) 100%);
    }

    .calculator-card,
    .card {
        background: linear-gradient(145deg, var(--gray-100) 0%, var(--gray-50) 100%);
        border-color: var(--gray-300);
    }

    .result-box {
        background: linear-gradient(135deg, var(--gray-100) 0%, var(--gray-50) 100%);
        border-color: var(--gray-300);
    }

    .input-group input,
    .input-group select {
        background: var(--gray-100);
        border-color: var(--gray-300);
        color: var(--gray-800);
    }

    /* Enhanced button styles for dark mode */
    .calc-btn {
        background: linear-gradient(135deg, var(--primary-400) 0%, var(--primary-500) 100%);
        color: var(--gray-50);
    }

    .calc-btn:hover {
        background: linear-gradient(135deg, var(--primary-300) 0%, var(--primary-400) 100%);
    }

    /* Copy button dark mode */
    .copy-btn {
        background: var(--gray-200);
        border-color: var(--gray-400);
        color: var(--gray-700);
    }

    .copy-btn:hover {
        background: var(--gray-300);
        color: var(--gray-800);
    }

    /* Skip link dark mode */
    .skip-link {
        background: var(--primary-500);
    }

    /* ES usage hint dark mode */
    .es-usage-hint {
        background: linear-gradient(135deg, var(--accent-300) 0%, var(--accent-400) 100%);
    }

    /* Nav tabs dark mode */
    .nav-tab {
        color: var(--gray-700);
    }

    .nav-tab.active {
        background: var(--primary-500);
        color: var(--gray-50);
    }

    /* Module header dark mode */
    .module-header {
        background: linear-gradient(135deg, var(--primary-400) 0%, var(--accent-400) 100%);
    }

    /* Stats accordion dark mode */
    .accordion-header {
        background: var(--gray-200);
        color: var(--gray-800);
    }

    .accordion-header:hover {
        background: var(--gray-300);
    }

    /* GRADE level cards dark mode */
    .grade-high { background: linear-gradient(135deg, #065f46 0%, #047857 100%); }
    .grade-moderate { background: linear-gradient(135deg, #92400e 0%, #b45309 100%); }
    .grade-low { background: linear-gradient(135deg, #c2410c 0%, #ea580c 100%); }
    .grade-very-low { background: linear-gradient(135deg, #991b1b 0%, #dc2626 100%); }

    /* RoB domain cards dark mode */
    .domain-card {
        background: var(--gray-100);
        border-color: var(--gray-300);
    }

    .domain-card:hover {
        background: var(--gray-200);
    }
}

/* Reduced motion for users who prefer it */
@media (prefers-reduced-motion: reduce) {
    *,
    *::before,
    *::after {
        animation-duration: 0.01ms !important;
        animation-iteration-count: 1 !important;
        transition-duration: 0.01ms !important;
    }
    
    .tab-content {
        animation: none;
    }
    
    .calculator-card:hover {
        transform: none;
    }
    
    .btn:hover {
        transform: none;
    }
}

/* Batch Processing Styles */
.batch-processing {
    max-width: 1000px;
    margin: 0 auto;
}

.upload-section {
    display: grid;
    grid-template-columns: 1fr 1fr;
    gap: 2rem;
    margin-bottom: 2rem;
}

.upload-card {
    background: white;
    border-radius: 12px;
    padding: 2rem;
    box-shadow: 0 4px 15px rgba(0,0,0,0.1);
    text-align: center;
}

.file-upload-area {
    border: 3px dashed var(--gray-200);
    border-radius: 12px;
    padding: 3rem 2rem;
    margin: 1rem 0;
    cursor: pointer;
    transition: all 0.3s ease;
    background: var(--gray-50);
}

.file-upload-area:hover {
    border-color: var(--primary-600);
    background: var(--primary-50);
}

.file-upload-area i {
    font-size: 3rem;
    color: var(--gray-500);
    margin-bottom: 1rem;
    display: block;
}

.file-upload-area p {
    margin: 0.5rem 0;
    color: var(--gray-500);
}

.file-info {
    font-size: 0.85rem !important;
    opacity: 0.8;
}

.template-section h3 {
    margin-bottom: 1rem;
    color: var(--gray-600);
}

.template-buttons {
    display: flex;
    flex-direction: column;
    gap: 0.5rem;
}

.template-btn {
    margin-bottom: 0.5rem;
}

/* Table Styles */
.table-container {
    overflow-x: auto;
    margin: 1rem 0;
}

.table-container table {
    width: 100%;
    border-collapse: collapse;
    background: white;
    border-radius: 8px;
    overflow: hidden;
    box-shadow: 0 2px 10px rgba(0,0,0,0.1);
}

.table-container th,
.table-container td {
    padding: 0.75rem;
    text-align: left;
    border-bottom: 1px solid var(--gray-200);
}

.table-container th {
    background: var(--gray-50);
    font-weight: 600;
    color: var(--gray-600);
}

.table-container tr:hover {
    background: var(--gray-50);
}

.batch-controls {
    display: flex;
    gap: 1rem;
    justify-content: center;
    margin-top: 1rem;
}

.batch-controls button {
    width: auto;
    margin-bottom: 0;
}

/* Reference Styles */
.reference-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(300px, 1fr));
    gap: 2rem;
}

.reference-card {
    background: white;
    border-radius: 12px;
    padding: 1.5rem;
    box-shadow: 0 4px 15px rgba(0,0,0,0.1);
}

.reference-card h3 {
    color: var(--gray-600);
    margin-bottom: 1rem;
    display: flex;
    align-items: center;
    gap: 0.5rem;
}

.reference-list {
    display: flex;
    flex-direction: column;
    gap: 1rem;
}

.reference-item {
    padding: 1rem;
    background: var(--gray-50);
    border-radius: 8px;
    border-left: 4px solid var(--primary-600);
}

.reference-item strong {
    color: var(--gray-600);
}

/* Method Accordion */
.method-accordion {
    display: flex;
    flex-direction: column;
    gap: 0.5rem;
}

.method-item {
    border: 1px solid var(--gray-200);
    border-radius: 8px;
    overflow: hidden;
}

.method-header {
    background: var(--gray-50);
    padding: 1rem;
    cursor: pointer;
    display: flex;
    justify-content: space-between;
    align-items: center;
    font-weight: 500;
    transition: background-color 0.3s ease;
}

.method-header:hover {
    background: var(--gray-200);
}

.method-content {
    padding: 1rem;
    display: none;
    background: white;
    border-top: 1px solid var(--gray-200);
}

.method-content.active {
    display: block;
}

.method-content p {
    margin-bottom: 0.5rem;
}

.method-content strong {
    color: var(--gray-600);
}

.tool-info {
    background: var(--gray-50);
    padding: 1rem;
    border-radius: 8px;
}

.tool-info p {
    margin-bottom: 0.5rem;
}

/* Modal Styles */
.modal {
    display: none;
    position: fixed;
    z-index: 1000;
    left: 0;
    top: 0;
    width: 100%;
    height: 100%;
    background-color: rgba(0,0,0,0.5);
    backdrop-filter: blur(5px);
}

.modal-content {
    background: white;
    margin: 5% auto;
    border-radius: 12px;
    width: 90%;
    max-width: 800px;
    max-height: 80vh;
    overflow-y: auto;
    box-shadow: 0 10px 30px rgba(0,0,0,0.3);
}

.modal-header {
    padding: 1.5rem;
    border-bottom: 1px solid var(--gray-200);
    display: flex;
    justify-content: space-between;
    align-items: center;
    background: var(--gray-50);
    border-radius: 12px 12px 0 0;
}

.modal-header h3 {
    margin: 0;
    color: var(--gray-600);
}

.close {
    font-size: 1.5rem;
    font-weight: bold;
    cursor: pointer;
    color: var(--gray-500);
    transition: color 0.3s ease;
}

.close:hover {
    color: var(--gray-600);
}

.modal-body {
    padding: 2rem;
}

/* Footer */
.footer {
    background: linear-gradient(135deg, var(--gray-800) 0%, var(--gray-900) 100%);
    color: white;
    text-align: center;
    padding: var(--space-12) 0;
    margin-top: var(--space-16);
    position: relative;
    overflow: hidden;
}

.footer::before {
    content: '';
    position: absolute;
    top: 0;
    left: 0;
    right: 0;
    bottom: 0;
    background: url("data:image/svg+xml,%3csvg xmlns='http://www.w3.org/2000/svg' viewBox='0 0 32 32' width='32' height='32' fill='none' stroke='%23ffffff08'%3e%3cpath d='m0 2 30 30m2-30L2 32'/%3e%3c/svg%3e");
    opacity: 0.3;
}

.footer p {
    margin: 0;
    color: white;
    opacity: 0.9;
    position: relative;
    z-index: 1;
    font-size: 0.9rem;
    letter-spacing: 0.025em;
}

.footer a {
    color: #87CEEB;
    text-decoration: none;
}

.footer a:hover {
    color: #B0E0E6;
    text-decoration: underline;
}

/* Responsive Design */
@media (max-width: 768px) {
    .container {
        padding: 0 15px;
    }
    
    .header h1 {
        font-size: 2rem;
    }
    
    .subtitle {
        font-size: 1rem;
    }
    
    .calculator-grid {
        grid-template-columns: 1fr;
        gap: 1.5rem;
    }
    
    .upload-section {
        grid-template-columns: 1fr;
        gap: 1.5rem;
    }
    
    .reference-grid {
        grid-template-columns: 1fr;
    }
    
    .nav-tabs .container {
        padding: 0 10px;
    }
    
    .tab-btn {
        padding: 0.75rem 1rem;
        font-size: 0.85rem;
    }
    
    .input-row {
        grid-template-columns: 1fr;
        gap: 0.5rem;
    }
    
    .batch-controls {
        flex-direction: column;
    }
    
    .modal-content {
        width: 95%;
        margin: 10% auto;
    }
    
    .modal-body {
        padding: 1rem;
    }
}

@media (max-width: 480px) {
    .header {
        padding: 1.5rem 0;
    }
    
    .header h1 {
        font-size: 1.5rem;
    }
    
    .module-header {
        padding: 1.5rem;
    }
    
    .module-header h2 {
        font-size: 1.5rem;
    }
    
    .calculator-card {
        padding: 1rem;
    }
    
    .tab-btn {
        padding: 0.5rem 0.75rem;
        font-size: 0.8rem;
    }
    
    .tab-btn i {
        display: none;
    }
}

/* Print Styles */
@media print {
    .nav-tabs,
    .formula-btn,
    .calc-btn,
    .upload-btn,
    .template-btn,
    .download-btn {
        display: none !important;
    }
    
    .calculator-card {
        break-inside: avoid;
        box-shadow: none;
        border: 1px solid var(--gray-300);
    }
    
    .main-content {
        padding: 1rem 0;
    }
}

/* Animations */
@keyframes fadeIn {
    from {
        opacity: 0;
        transform: translateY(10px);
    }
    to {
        opacity: 1;
        transform: translateY(0);
    }
}

.tab-content.active {
    animation: fadeIn 0.3s ease;
}

.calculator-card {
    animation: fadeIn 0.5s ease;
}

/* Accessibility */
.input-group input:focus,
.input-group select:focus,
.calc-btn:focus,
.tab-btn:focus {
    outline: 2px solid var(--primary-600);
    outline-offset: 2px;
}

/* Loading States */
.loading {
    position: relative;
    pointer-events: none;
}

.loading::after {
    content: '';
    position: absolute;
    top: 50%;
    left: 50%;
    width: 20px;
    height: 20px;
    margin: -10px 0 0 -10px;
    border: 2px solid var(--gray-100);
    border-top: 2px solid var(--primary-600);
    border-radius: 50%;
    animation: spin 1s linear infinite;
}

@keyframes spin {
    0% { transform: rotate(0deg); }
    100% { transform: rotate(360deg); }
}

/* Guide Section Styles */
.guide-content {
    padding: 2rem 0;
}

.guide-section {
    margin-bottom: 3rem;
}

.guide-section h3 {
    color: var(--gray-600);
    margin-bottom: 1.5rem;
    display: flex;
    align-items: center;
    gap: 0.5rem;
}

.guide-card {
    background: white;
    border-radius: 12px;
    padding: 1.5rem;
    box-shadow: 0 2px 10px rgba(0,0,0,0.08);
    margin-bottom: 1.5rem;
}

.guide-card h4 {
    color: var(--primary-600);
    margin-bottom: 1rem;
}

.guide-steps {
    counter-reset: step-counter;
    list-style: none;
    padding-left: 0;
}

.guide-steps li {
    counter-increment: step-counter;
    position: relative;
    padding-left: 3rem;
    margin-bottom: 1rem;
    line-height: 1.8;
}

.guide-steps li::before {
    content: counter(step-counter);
    position: absolute;
    left: 0;
    top: 0;
    background: var(--primary-600);
    color: white;
    width: 2rem;
    height: 2rem;
    border-radius: 50%;
    display: flex;
    align-items: center;
    justify-content: center;
    font-weight: bold;
}


/* Module Overview Cards */
.module-overview {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));
    gap: 1.5rem;
    margin-top: 1rem;
}

.overview-card {
    background: white;
    border-radius: 12px;
    padding: 1.5rem;
    box-shadow: 0 4px 15px rgba(0,0,0,0.1);
    transition: transform 0.3s ease;
}

.overview-card:hover {
    transform: translateY(-2px);
    box-shadow: 0 6px 20px rgba(0,0,0,0.15);
}

.overview-icon {
    font-size: 2rem;
    color: var(--primary-600);
    margin-bottom: 1rem;
}

.overview-card h4 {
    color: var(--gray-600);
    margin-bottom: 0.5rem;
}

.overview-card p {
    color: var(--gray-500);
    margin-bottom: 1rem;
}

.when-to-use {
    background: var(--primary-50);
    padding: 0.75rem;
    border-radius: 8px;
    border-left: 3px solid var(--primary-600);
    font-size: 0.9rem;
}

/* Tips Grid */
.tips-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(250px, 1fr));
    gap: 1.5rem;
}

.tip-card {
    background: white;
    border-radius: 12px;
    padding: 1.5rem;
    box-shadow: 0 2px 10px rgba(0,0,0,0.08);
}

.tip-icon {
    font-size: 2rem;
    margin-bottom: 1rem;
}

.tip-icon .fa-check-circle {
    color: var(--success);
}

.tip-icon .fa-exclamation-triangle {
    color: var(--warning);
}

.tip-icon .fa-chart-line {
    color: var(--info);
}

.tip-card h4 {
    color: var(--gray-600);
    margin-bottom: 1rem;
}

.tip-card ul {
    list-style: none;
    padding-left: 0;
}

.tip-card li {
    padding-left: 1.5rem;
    position: relative;
    margin-bottom: 0.5rem;
}

.tip-card li::before {
    content: "•";
    position: absolute;
    left: 0.5rem;
    color: var(--primary-600);
}

/* FAQ Styles */
.faq-container {
    margin-top: 1rem;
}

.faq-item {
    background: white;
    border-radius: 12px;
    padding: 1.5rem;
    margin-bottom: 1rem;
    box-shadow: 0 2px 10px rgba(0,0,0,0.08);
}

.faq-item h4 {
    color: var(--primary-600);
    margin-bottom: 0.75rem;
}

.faq-item p {
    color: var(--gray-600);
    line-height: 1.6;
}

/* Usage Guide Styles */
.usage-guide {
    background: var(--gray-50);
    border-radius: 12px;
    padding: 1.5rem;
    margin: 2rem 0;
    border: 1px solid var(--gray-200);
}

.usage-header {
    display: flex;
    align-items: center;
    gap: 0.75rem;
    margin-bottom: 1.5rem;
}

.usage-header i {
    font-size: 1.5rem;
    color: var(--primary-600);
}

.usage-header h3 {
    margin: 0;
    color: var(--gray-600);
}

.usage-content {
    display: grid;
    grid-template-columns: 1fr 1fr;
    gap: 2rem;
}

.usage-scenario h4,
.usage-examples h4,
.usage-tips h4 {
    color: var(--gray-600);
    margin-bottom: 1rem;
    font-size: 1rem;
}

.usage-scenario ul {
    list-style: none;
    padding-left: 0;
}

.usage-scenario li {
    padding-left: 1.5rem;
    position: relative;
    margin-bottom: 0.75rem;
    line-height: 1.6;
}

.usage-scenario li::before {
    content: "▸";
    position: absolute;
    left: 0;
    color: var(--primary-600);
    font-weight: bold;
}

.example-case {
    background: white;
    padding: 1rem;
    border-radius: 8px;
    margin-bottom: 0.75rem;
    border-left: 3px solid var(--primary-600);
}

.example-tag {
    background: var(--primary-600);
    color: white;
    padding: 0.25rem 0.5rem;
    border-radius: 4px;
    font-size: 0.8rem;
    font-weight: bold;
    margin-right: 0.5rem;
}

.tip-box {
    background: white;
    padding: 1rem;
    border-radius: 8px;
    margin-bottom: 0.75rem;
    display: flex;
    align-items: flex-start;
    gap: 0.75rem;
}

.tip-box i {
    color: var(--primary-600);
    margin-top: 0.2rem;
}

/* Statistics Module Styles */
.stats-content {
    padding: 2rem 0;
}

.stats-section {
    margin-bottom: 3rem;
}

.stats-section h3 {
    color: var(--gray-600);
    margin-bottom: 1.5rem;
    display: flex;
    align-items: center;
    gap: 0.5rem;
}

/* Decision Flow Styles */
.decision-card {
    background: white;
    border-radius: 12px;
    padding: 2rem;
    box-shadow: 0 4px 15px rgba(0,0,0,0.1);
}

.decision-flow {
    display: flex;
    flex-direction: column;
    align-items: center;
}

.decision-box {
    background: var(--gray-50);
    border-radius: 8px;
    padding: 1.5rem;
    text-align: center;
    max-width: 300px;
    border: 2px solid var(--gray-200);
}

.decision-box.primary {
    background: linear-gradient(135deg, var(--primary-600) 0%, var(--accent-600) 100%);
    color: white;
    border: none;
}

.decision-box.success {
    background: #d4edda;
    border-color: #c3e6cb;
    color: #155724;
}

.decision-box.warning {
    background: #fff3cd;
    border-color: #ffeaa7;
    color: #856404;
}

.decision-box.result {
    background: #e7f3ff;
    border-color: var(--primary-600);
    color: #004085;
}

.decision-arrow {
    font-size: 2rem;
    color: var(--primary-600);
    margin: 1rem 0;
}

.decision-branches {
    display: flex;
    gap: 4rem;
    justify-content: center;
}

.branch-left, .branch-right {
    display: flex;
    flex-direction: column;
    align-items: center;
}

/* Model Grid */
.model-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));
    gap: 1.5rem;
}

.model-card {
    background: white;
    border-radius: 12px;
    padding: 1.5rem;
    box-shadow: 0 2px 10px rgba(0,0,0,0.08);
}

.model-card h4 {
    color: var(--gray-600);
    margin-bottom: 1rem;
    font-size: 1.1rem;
}

.model-card ul {
    list-style: none;
    padding-left: 0;
}

.model-card li {
    padding-left: 1.5rem;
    position: relative;
    margin-bottom: 0.5rem;
    line-height: 1.6;
}

.model-card li::before {
    content: "•";
    position: absolute;
    left: 0.5rem;
    color: var(--primary-600);
}

.formula-box {
    background: var(--primary-50);
    padding: 1rem;
    border-radius: 8px;
    text-align: center;
    font-family: 'Courier New', monospace;
}

.formula-note {
    font-size: 0.85rem;
    color: var(--gray-500);
    margin-top: 0.5rem;
}

.pros-cons {
    display: flex;
    flex-direction: column;
    gap: 1rem;
}

.pros, .cons {
    padding: 0.75rem;
    border-radius: 6px;
}

.pros {
    background: #d4edda;
}

.cons {
    background: #f8d7da;
}

.pros strong {
    color: #155724;
}

.cons strong {
    color: #721c24;
}

.pros ul, .cons ul {
    margin-top: 0.5rem;
}

/* Heterogeneity Grid */
.heterogeneity-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(300px, 1fr));
    gap: 1.5rem;
}

.hetero-card {
    background: white;
    border-radius: 12px;
    padding: 1.5rem;
    box-shadow: 0 4px 15px rgba(0,0,0,0.1);
}

.hetero-icon {
    font-size: 2rem;
    color: var(--primary-600);
    margin-bottom: 1rem;
    text-align: center;
}

.hetero-card h4 {
    color: var(--gray-600);
    margin-bottom: 1rem;
    text-align: center;
}

.hetero-content {
    font-size: 0.95rem;
}

.interpretation {
    background: var(--gray-50);
    padding: 1rem;
    border-radius: 8px;
    margin-top: 1rem;
}

.interpretation h5 {
    color: var(--gray-600);
    margin-bottom: 0.5rem;
    font-size: 0.9rem;
}

.badge {
    display: inline-block;
    padding: 0.25rem 0.5rem;
    border-radius: 4px;
    font-size: 0.8rem;
    font-weight: bold;
    margin-right: 0.5rem;
}

.badge.low {
    background: #d4edda;
    color: #155724;
}

.badge.moderate {
    background: #fff3cd;
    color: #856404;
}

.badge.high {
    background: #f8d7da;
    color: #721c24;
}

.badge.very-high {
    background: #721c24;
    color: white;
}

/* Method Accordion */
.method-accordion {
    display: flex;
    flex-direction: column;
    gap: 1rem;
}

.method-item {
    background: white;
    border-radius: 12px;
    box-shadow: 0 2px 10px rgba(0,0,0,0.08);
    overflow: hidden;
}

.method-header {
    background: var(--gray-50);
    padding: 1.25rem;
    cursor: pointer;
    display: flex;
    justify-content: space-between;
    align-items: center;
    transition: background-color 0.3s ease;
}

.method-header:hover {
    background: var(--gray-200);
}

.method-header span {
    display: flex;
    align-items: center;
    gap: 0.75rem;
    font-weight: 600;
    color: var(--gray-600);
}

.method-content {
    padding: 1.5rem;
    display: none;
    background: white;
}

.method-content.active {
    display: block;
}

.method-content h5 {
    color: var(--primary-600);
    margin-bottom: 0.5rem;
    margin-top: 1rem;
}

.method-content h5:first-child {
    margin-top: 0;
}

.method-content ul {
    list-style: none;
    padding-left: 0;
}

.method-content li {
    padding-left: 1.5rem;
    position: relative;
    margin-bottom: 0.5rem;
}

.method-content li::before {
    content: "▸";
    position: absolute;
    left: 0;
    color: var(--primary-600);
}

/* Recommendation Table */
.recommendation-table {
    overflow-x: auto;
    margin-top: 1rem;
}

.recommendation-table table {
    width: 100%;
    background: white;
    border-radius: 12px;
    overflow: hidden;
    box-shadow: 0 4px 15px rgba(0,0,0,0.1);
}

.recommendation-table th,
.recommendation-table td {
    padding: 1rem;
    text-align: left;
    border-bottom: 1px solid var(--gray-200);
}

.recommendation-table th {
    background: linear-gradient(135deg, var(--primary-600) 0%, var(--accent-600) 100%);
    color: white;
    font-weight: 600;
}

.recommendation-table tr:hover {
    background: var(--gray-50);
}

.recommendation-table tr:last-child td {
    border-bottom: none;
}

/* Outcome Methods Styles */
.outcome-methods {
    margin-top: 2rem;
    padding: 1.5rem;
    background: var(--gray-50);
    border-radius: 12px;
    border: 1px solid var(--gray-200);
}

.outcome-methods h4 {
    color: var(--gray-600);
    margin-bottom: 1.5rem;
    display: flex;
    align-items: center;
    gap: 0.5rem;
}

.outcome-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(300px, 1fr));
    gap: 1.5rem;
}

.outcome-card {
    background: white;
    border-radius: 8px;
    overflow: hidden;
    box-shadow: 0 2px 8px rgba(0,0,0,0.08);
}

.outcome-header {
    background: linear-gradient(135deg, var(--primary-600) 0%, var(--accent-600) 100%);
    color: white;
    padding: 1rem;
}

.outcome-header h5 {
    margin: 0;
    display: flex;
    align-items: center;
    gap: 0.5rem;
}

.method-list {
    padding: 1rem;
}

.method-item-small {
    margin-bottom: 1rem;
    padding-bottom: 1rem;
    border-bottom: 1px solid #f1f1f1;
}

.method-item-small:last-child {
    border-bottom: none;
    margin-bottom: 0;
    padding-bottom: 0;
}

.method-item-small strong {
    color: var(--gray-600);
    display: block;
    margin-bottom: 0.25rem;
}

.method-item-small p {
    color: var(--gray-500);
    font-size: 0.9rem;
    line-height: 1.4;
    margin-bottom: 0.25rem;
}

.formula-small {
    font-family: 'Courier New', monospace;
    background: var(--primary-50);
    padding: 0.25rem 0.5rem;
    border-radius: 4px;
    font-size: 0.85rem;
    color: var(--gray-600);
    display: inline-block;
}

/* Tau Methods Styles */
.tau-methods {
    margin-top: 2rem;
    padding: 1.5rem;
    background: #fff3e0;
    border-radius: 12px;
    border: 1px solid #ffcc80;
}

.tau-methods h4 {
    color: var(--gray-600);
    margin-bottom: 1.5rem;
    display: flex;
    align-items: center;
    gap: 0.5rem;
}

.tau-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));
    gap: 1.5rem;
}

.tau-method-card {
    background: white;
    border-radius: 8px;
    padding: 1.5rem;
    box-shadow: 0 2px 8px rgba(0,0,0,0.08);
}

.tau-method-card h5 {
    color: #e65100;
    margin-bottom: 1rem;
    font-size: 1.1rem;
}

.tau-method-card ul {
    list-style: none;
    padding-left: 0;
}

.tau-method-card li {
    padding-left: 1.5rem;
    position: relative;
    margin-bottom: 0.5rem;
    line-height: 1.6;
    font-size: 0.9rem;
}

.tau-method-card li::before {
    content: "•";
    position: absolute;
    left: 0.5rem;
    color: #ff9800;
}

/* Checklist Styles */
.checklist-container {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(250px, 1fr));
    gap: 2rem;
    background: white;
    padding: 2rem;
    border-radius: 12px;
    box-shadow: 0 4px 15px rgba(0,0,0,0.1);
}

.checklist-column h4 {
    color: var(--primary-600);
    margin-bottom: 1rem;
    padding-bottom: 0.5rem;
    border-bottom: 2px solid var(--gray-200);
}

.checklist-item {
    display: flex;
    align-items: center;
    margin-bottom: 0.75rem;
    cursor: pointer;
    padding: 0.5rem;
    border-radius: 6px;
    transition: background-color 0.3s ease;
}

.checklist-item:hover {
    background: var(--gray-50);
}

.checklist-item input[type="checkbox"] {
    width: 1.2rem;
    height: 1.2rem;
    margin-right: 0.75rem;
    cursor: pointer;
}

.checklist-item span {
    color: var(--gray-600);
    font-size: 0.95rem;
}

.checklist-item input[type="checkbox"]:checked + span {
    color: var(--success);
    text-decoration: line-through;
}

/* Responsive adjustments */
@media (max-width: 768px) {
    .usage-content {
        grid-template-columns: 1fr;
        gap: 1.5rem;
    }
    
    .module-overview {
        grid-template-columns: 1fr;
    }
    
    .tips-grid {
        grid-template-columns: 1fr;
    }
    
    .decision-branches {
        flex-direction: column;
        gap: 2rem;
    }
    
    .model-grid {
        grid-template-columns: 1fr;
    }
    
    .heterogeneity-grid {
        grid-template-columns: 1fr;
    }
    
    .checklist-container {
        grid-template-columns: 1fr;
    }
    
    .recommendation-table {
        font-size: 0.85rem;
    }
    
    .recommendation-table th,
    .recommendation-table td {
        padding: 0.5rem;
    }
}

/* Utility Classes */
.text-center {
    text-align: center;
}

.text-left {
    text-align: left;
}

.text-right {
    text-align: right;
}

.mb-1 {
    margin-bottom: 0.5rem;
}

.mb-2 {
    margin-bottom: 1rem;
}

.mb-3 {
    margin-bottom: 1.5rem;
}

.mt-1 {
    margin-top: 0.5rem;
}

.mt-2 {
    margin-top: 1rem;
}

.mt-3 {
    margin-top: 1.5rem;
}

.hidden {
    display: none !important;
}

.visible {
    display: block !important;
}

/* Cochrane Heterogeneity Assessment Styles */
.heterogeneity-guide {
    display: flex;
    flex-direction: column;
    gap: 2rem;
}

.heterogeneity-card {
    background: white;
    border-radius: 12px;
    padding: 2rem;
    box-shadow: 0 4px 12px rgba(0,0,0,0.1);
    border: 1px solid var(--gray-200);
}

.heterogeneity-card h4 {
    color: var(--gray-600);
    margin-bottom: 1.5rem;
    display: flex;
    align-items: center;
    gap: 0.5rem;
}

/* I² Scale Visualization */
.i-squared-scale {
    display: flex;
    flex-direction: column;
    gap: 1rem;
    margin-bottom: 2rem;
}

.scale-item {
    display: flex;
    align-items: center;
    padding: 1rem;
    border-radius: 8px;
    border-left: 4px solid;
    background: var(--gray-50);
    transition: all 0.3s ease;
}

.scale-item:hover {
    transform: translateX(5px);
    box-shadow: 0 2px 8px rgba(0,0,0,0.1);
}

.scale-item.low {
    border-left-color: var(--success);
    background: #f0fff4;
}

.scale-item.moderate {
    border-left-color: var(--warning);
    background: #fffbf0;
}

.scale-item.substantial {
    border-left-color: #fd7e14;
    background: #fff5f0;
}

.scale-item.considerable {
    border-left-color: #dc3545;
    background: #fff0f0;
}

.scale-range {
    font-weight: bold;
    font-size: 1.1rem;
    color: var(--gray-600);
    min-width: 100px;
}

.scale-label {
    font-weight: 600;
    margin: 0 1rem;
    min-width: 120px;
}

.scale-note {
    color: var(--gray-500);
    font-size: 0.9rem;
    flex: 1;
}

/* Cochrane Note */
.cochrane-note {
    background: #e3f2fd;
    border: 1px solid #bbdefb;
    border-radius: 8px;
    padding: 1.5rem;
    margin-top: 1.5rem;
}

.cochrane-note p {
    margin-bottom: 1rem;
    color: #1565c0;
}

.cochrane-note ul {
    list-style: none;
    padding-left: 0;
}

.cochrane-note li {
    position: relative;
    padding-left: 1.5rem;
    margin-bottom: 0.5rem;
    color: var(--gray-600);
}

.cochrane-note li::before {
    content: "▸";
    position: absolute;
    left: 0;
    color: #1565c0;
    font-weight: bold;
}

/* Statistics Grid */
.stats-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(250px, 1fr));
    gap: 1.5rem;
}

.stat-item {
    display: flex;
    align-items: flex-start;
    gap: 1rem;
    padding: 1.5rem;
    background: var(--gray-50);
    border-radius: 8px;
    border: 1px solid var(--gray-200);
}

.stat-symbol {
    font-size: 2rem;
    font-weight: bold;
    color: var(--primary-600);
    font-family: 'Times New Roman', serif;
    min-width: 50px;
    text-align: center;
    background: var(--primary-50);
    padding: 0.5rem;
    border-radius: 50%;
}

.stat-desc {
    flex: 1;
    line-height: 1.6;
    font-size: 0.9rem;
    color: var(--gray-600);
}

/* Enhanced Decision Flow */
.decision-card.enhanced {
    background: white;
    padding: 2rem;
    border-radius: 16px;
    color: var(--gray-800);
    box-shadow: 0 8px 24px rgba(0, 0, 0, 0.1);
    border: 1px solid var(--gray-200);
}

.decision-flow-enhanced {
    display: flex;
    flex-direction: column;
    gap: 2rem;
}

.decision-step {
    display: flex;
    justify-content: center;
}

.decision-branches-enhanced {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));
    gap: 2rem;
    margin-top: 1rem;
}

.branch-column {
    display: flex;
    flex-direction: column;
    align-items: center;
    gap: 1rem;
}

.decision-box {
    background: rgba(255, 255, 255, 0.95);
    color: var(--gray-600);
    padding: 1.5rem;
    border-radius: 12px;
    box-shadow: 0 4px 12px rgba(0, 0, 0, 0.1);
    width: 100%;
    text-align: center;
    transition: transform 0.3s ease, box-shadow 0.3s ease;
}

.decision-box:hover {
    transform: translateY(-2px);
    box-shadow: 0 6px 20px rgba(0, 0, 0, 0.15);
}

.decision-box h4 {
    margin-bottom: 1rem;
    color: var(--gray-600);
    font-weight: 600;
}

.decision-box ul {
    list-style: none;
    padding: 0;
    text-align: left;
}

.decision-box li {
    position: relative;
    padding-left: 1.2rem;
    margin-bottom: 0.5rem;
    font-size: 0.9rem;
}

.decision-box li::before {
    content: "•";
    position: absolute;
    left: 0;
    font-weight: bold;
}

.decision-box.success li::before {
    color: var(--success);
}

.decision-box.warning li::before {
    color: var(--warning);
}

.decision-box.danger li::before {
    color: #dc3545;
}

.decision-box.result {
    font-weight: bold;
    border: 2px solid;
}

.decision-box.result.success {
    border-color: var(--success);
    background: linear-gradient(135deg, #d4edda, #c3e6cb);
}

.decision-box.result.warning {
    border-color: var(--warning);
    background: linear-gradient(135deg, #fff3cd, #ffeaa7);
}

.decision-box.result.danger {
    border-color: #dc3545;
    background: linear-gradient(135deg, #f8d7da, #f5c6cb);
}

/* GRADE System Styles */
.grade-overview {
    display: flex;
    flex-direction: column;
    gap: 3rem;
}

.grade-intro {
    background: var(--gray-50);
    padding: 2rem;
    border-radius: 12px;
    border-left: 4px solid var(--primary-600);
}

.grade-intro p {
    font-size: 1.1rem;
    line-height: 1.6;
    color: var(--gray-600);
    margin: 0;
}

/* GRADE Quality Levels */
.grade-levels {
    background: white;
    border-radius: 12px;
    padding: 2rem;
    box-shadow: 0 4px 12px rgba(0,0,0,0.1);
}

.grade-levels h4 {
    color: var(--gray-600);
    margin-bottom: 2rem;
    display: flex;
    align-items: center;
    gap: 0.5rem;
}

.grade-scale {
    display: flex;
    flex-direction: column;
    gap: 1.5rem;
}

.grade-item {
    display: flex;
    align-items: center;
    padding: 1.5rem;
    border-radius: 12px;
    gap: 2rem;
    transition: transform 0.3s ease, box-shadow 0.3s ease;
}

.grade-item:hover {
    transform: translateX(5px);
    box-shadow: 0 4px 16px rgba(0,0,0,0.1);
}

.grade-item.very-high {
    background: linear-gradient(135deg, #d4edda, #c3e6cb);
    border: 2px solid var(--success);
}

.grade-item.high {
    background: linear-gradient(135deg, #cce5ff, #b3d9ff);
    border: 2px solid #007bff;
}

.grade-item.moderate {
    background: linear-gradient(135deg, #fff3cd, #ffeaa7);
    border: 2px solid var(--warning);
}

.grade-item.low {
    background: linear-gradient(135deg, #f8d7da, #f5c6cb);
    border: 2px solid #dc3545;
}

.grade-circle {
    font-size: 2rem;
    font-weight: bold;
    color: var(--gray-600);
    min-width: 120px;
    text-align: center;
    background: white;
    padding: 1rem;
    border-radius: 50%;
    box-shadow: 0 2px 8px rgba(0,0,0,0.1);
}

.grade-content {
    flex: 1;
}

.grade-content h5 {
    color: var(--gray-600);
    margin-bottom: 0.5rem;
    font-size: 1.2rem;
}

.grade-content p {
    color: var(--gray-600);
    margin-bottom: 0.5rem;
    font-weight: 500;
}

.grade-note {
    font-size: 0.9rem;
    color: var(--gray-500);
    font-style: italic;
}

/* GRADE Factors */
.grade-factors {
    background: white;
    border-radius: 12px;
    padding: 2rem;
    box-shadow: 0 4px 12px rgba(0,0,0,0.1);
}

.grade-factors h4 {
    color: var(--gray-600);
    margin-bottom: 2rem;
    display: flex;
    align-items: center;
    gap: 0.5rem;
}

.factors-grid {
    display: grid;
    grid-template-columns: 2fr 1fr;
    gap: 2rem;
}

.factor-group {
    padding: 1.5rem;
    border-radius: 12px;
    border: 2px solid;
}

.factor-group.downgrade {
    border-color: #dc3545;
    background: #fff5f5;
}

.factor-group.upgrade {
    border-color: var(--success);
    background: #f0fff4;
}

.factor-group h5 {
    color: var(--gray-600);
    margin-bottom: 1.5rem;
    display: flex;
    align-items: center;
    gap: 0.5rem;
    font-size: 1.1rem;
}

.factor-list {
    display: flex;
    flex-direction: column;
    gap: 1.5rem;
}

.factor-item {
    display: flex;
    gap: 1rem;
    background: white;
    padding: 1.5rem;
    border-radius: 8px;
    box-shadow: 0 2px 8px rgba(0,0,0,0.05);
}

.factor-icon {
    font-size: 1.5rem;
    color: var(--primary-600);
    min-width: 40px;
    text-align: center;
}

.factor-content {
    flex: 1;
}

.factor-content h6 {
    color: var(--gray-600);
    margin-bottom: 0.75rem;
    font-size: 1rem;
    font-weight: 600;
}

.factor-content ul {
    list-style: none;
    padding: 0;
    margin: 0;
}

.factor-content li {
    position: relative;
    padding-left: 1.2rem;
    margin-bottom: 0.5rem;
    font-size: 0.9rem;
    color: var(--gray-500);
}

.factor-content li::before {
    content: "▸";
    position: absolute;
    left: 0;
    color: var(--primary-600);
    font-weight: bold;
}

/* GRADE Decision Tree */
.grade-decision-tree {
    background: white;
    border-radius: 12px;
    padding: 2rem;
    box-shadow: 0 4px 12px rgba(0,0,0,0.1);
}

.grade-decision-tree h4 {
    color: var(--gray-600);
    margin-bottom: 2rem;
    display: flex;
    align-items: center;
    gap: 0.5rem;
}

.decision-tree {
    display: flex;
    flex-direction: column;
    align-items: center;
    gap: 1.5rem;
}

.tree-step {
    width: 100%;
    display: flex;
    justify-content: center;
}

.tree-box {
    background: var(--gray-50);
    padding: 1.5rem;
    border-radius: 12px;
    border: 2px solid var(--gray-200);
    min-width: 300px;
    text-align: center;
}

.tree-box.start {
    background: linear-gradient(135deg, var(--primary-600), var(--accent-600));
    color: white;
    border-color: var(--primary-600);
}

.tree-box.evaluation {
    background: linear-gradient(135deg, var(--warning), #ffb300);
    color: var(--gray-600);
    border-color: var(--warning);
}

.tree-box.upgrade {
    background: linear-gradient(135deg, var(--success), #20c997);
    color: white;
    border-color: var(--success);
}

.tree-box.final {
    background: linear-gradient(135deg, #dc3545, #e83e8c);
    color: white;
    border-color: #dc3545;
}

.tree-box h5 {
    margin-bottom: 1rem;
    font-weight: 600;
}

.tree-box p {
    margin: 0;
    font-size: 0.9rem;
}

.tree-branches {
    display: flex;
    flex-direction: column;
    gap: 1rem;
    margin-top: 1rem;
}

.branch {
    display: flex;
    justify-content: space-between;
    align-items: center;
    padding: 0.75rem;
    background: rgba(255,255,255,0.9);
    border-radius: 8px;
    color: var(--gray-600);
}

.initial-grade {
    font-weight: bold;
    font-size: 1.1rem;
}

.initial-grade.high {
    color: var(--success);
}

.initial-grade.low {
    color: #dc3545;
}

.tree-arrow {
    font-size: 2rem;
    color: var(--primary-600);
    font-weight: bold;
}

/* Effect Measures Guide Styles */
.effect-measures-guide {
    display: flex;
    flex-direction: column;
    gap: 3rem;
}

/* Cochrane Principles */
.cochrane-principles {
    background: white;
    border-radius: 12px;
    padding: 2rem;
    box-shadow: 0 4px 12px rgba(0,0,0,0.1);
}

.cochrane-principles h4 {
    color: var(--gray-600);
    margin-bottom: 2rem;
    display: flex;
    align-items: center;
    gap: 0.5rem;
}

.principles-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(300px, 1fr));
    gap: 2rem;
}

.principle-card {
    background: var(--gray-50);
    border-radius: 12px;
    padding: 2rem;
    text-align: center;
    border: 2px solid var(--gray-200);
    transition: transform 0.3s ease, box-shadow 0.3s ease;
}

.principle-card:hover {
    transform: translateY(-5px);
    box-shadow: 0 8px 24px rgba(0,0,0,0.15);
    border-color: var(--primary-600);
}

.principle-icon {
    font-size: 3rem;
    color: var(--primary-600);
    margin-bottom: 1rem;
}

.principle-card h5 {
    color: var(--gray-600);
    margin-bottom: 1rem;
    font-size: 1.3rem;
}

.principle-card p {
    color: var(--gray-500);
    margin-bottom: 1.5rem;
    font-style: italic;
}

.principle-card ul {
    list-style: none;
    padding: 0;
    text-align: left;
}

.principle-card li {
    position: relative;
    padding-left: 1.2rem;
    margin-bottom: 0.5rem;
    color: var(--gray-600);
    font-size: 0.9rem;
}

.principle-card li::before {
    content: "▸";
    position: absolute;
    left: 0;
    color: var(--primary-600);
    font-weight: bold;
}

/* Continuous Effects */
.continuous-effects {
    background: white;
    border-radius: 12px;
    padding: 2rem;
    box-shadow: 0 4px 12px rgba(0,0,0,0.1);
}

.continuous-effects h4 {
    color: var(--gray-600);
    margin-bottom: 2rem;
    display: flex;
    align-items: center;
    gap: 0.5rem;
}

.effect-comparison {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(400px, 1fr));
    gap: 2rem;
}

.effect-measure-card {
    border-radius: 12px;
    padding: 2rem;
    border: 2px solid;
    transition: transform 0.3s ease, box-shadow 0.3s ease;
}

.effect-measure-card:hover {
    transform: translateY(-3px);
    box-shadow: 0 6px 20px rgba(0,0,0,0.1);
}

.effect-measure-card.md-card {
    border-color: var(--success);
    background: linear-gradient(135deg, #f0fff4, #d4edda);
}

.effect-measure-card.smd-card {
    border-color: #007bff;
    background: linear-gradient(135deg, #f0f8ff, #cce5ff);
}

.effect-header {
    display: flex;
    justify-content: space-between;
    align-items: center;
    margin-bottom: 1.5rem;
    padding-bottom: 1rem;
    border-bottom: 2px solid rgba(0,0,0,0.1);
}

.effect-header h5 {
    color: var(--gray-600);
    font-size: 1.2rem;
    margin: 0;
}

.effect-symbol {
    font-family: 'Times New Roman', serif;
    font-size: 1.1rem;
    font-weight: bold;
    color: var(--gray-600);
    background: white;
    padding: 0.5rem 1rem;
    border-radius: 8px;
    box-shadow: 0 2px 4px rgba(0,0,0,0.1);
}

.effect-details {
    display: flex;
    flex-direction: column;
    gap: 1.5rem;
}

.advantages, .limitations, .when-to-use {
    background: white;
    padding: 1.5rem;
    border-radius: 8px;
    box-shadow: 0 2px 8px rgba(0,0,0,0.05);
}

.advantages h6 {
    color: var(--success);
    margin-bottom: 1rem;
    display: flex;
    align-items: center;
    gap: 0.5rem;
}

.limitations h6 {
    color: #dc3545;
    margin-bottom: 1rem;
    display: flex;
    align-items: center;
    gap: 0.5rem;
}

.when-to-use h6 {
    color: var(--primary-600);
    margin-bottom: 1rem;
    display: flex;
    align-items: center;
    gap: 0.5rem;
}

.effect-details ul {
    list-style: none;
    padding: 0;
    margin: 0;
}

.effect-details li {
    position: relative;
    padding-left: 1.2rem;
    margin-bottom: 0.5rem;
    color: var(--gray-600);
    font-size: 0.9rem;
}

.effect-details li::before {
    content: "•";
    position: absolute;
    left: 0;
    color: var(--primary-600);
    font-weight: bold;
}

.interpretation-guide {
    background: #fff3cd;
    border: 1px solid #ffeaa7;
    border-radius: 8px;
    padding: 1.5rem;
}

.interpretation-guide h6 {
    color: var(--gray-600);
    margin-bottom: 1rem;
}

.cohen-scale {
    display: flex;
    gap: 1rem;
    flex-wrap: wrap;
}

.scale-item {
    background: white;
    padding: 0.5rem 1rem;
    border-radius: 20px;
    border: 2px solid;
    font-size: 0.9rem;
    font-weight: 600;
}

.scale-item.small {
    border-color: var(--success);
    color: var(--success);
}

.scale-item.medium {
    border-color: var(--warning);
    color: var(--warning);
}

.scale-item.large {
    border-color: #dc3545;
    color: #dc3545;
}

/* Binary Effects */
.binary-effects {
    background: white;
    border-radius: 12px;
    padding: 2rem;
    box-shadow: 0 4px 12px rgba(0,0,0,0.1);
}

.binary-effects h4 {
    color: var(--gray-600);
    margin-bottom: 2rem;
    display: flex;
    align-items: center;
    gap: 0.5rem;
}

.binary-measures-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(320px, 1fr));
    gap: 2rem;
}

.binary-measure-card {
    border-radius: 12px;
    padding: 2rem;
    border: 2px solid;
    transition: transform 0.3s ease, box-shadow 0.3s ease;
}

.binary-measure-card:hover {
    transform: translateY(-3px);
    box-shadow: 0 6px 20px rgba(0,0,0,0.1);
}

.binary-measure-card.or-card {
    border-color: #e83e8c;
    background: linear-gradient(135deg, #fff0f6, #f8d7da);
}

.binary-measure-card.rr-card {
    border-color: #fd7e14;
    background: linear-gradient(135deg, #fff8f0, #ffe4cc);
}

.binary-measure-card.rd-card {
    border-color: #6610f2;
    background: linear-gradient(135deg, #f8f0ff, #e2d9f3);
}

.measure-header {
    text-align: center;
    margin-bottom: 1.5rem;
    padding-bottom: 1rem;
    border-bottom: 2px solid rgba(0,0,0,0.1);
}

.measure-header h5 {
    color: var(--gray-600);
    margin-bottom: 0.5rem;
    font-size: 1.2rem;
}

.measure-formula {
    font-family: 'Times New Roman', serif;
    font-size: 1rem;
    font-weight: bold;
    background: white;
    padding: 0.5rem 1rem;
    border-radius: 8px;
    display: inline-block;
    box-shadow: 0 2px 4px rgba(0,0,0,0.1);
}

.measure-properties {
    display: flex;
    flex-direction: column;
    gap: 1rem;
}

.property-item {
    background: white;
    padding: 1rem;
    border-radius: 8px;
    font-size: 0.9rem;
    line-height: 1.5;
    box-shadow: 0 2px 8px rgba(0,0,0,0.05);
}

.property-item strong {
    color: var(--primary-600);
}

/* Survival Effects */
.survival-effects {
    background: white;
    border-radius: 12px;
    padding: 2rem;
    box-shadow: 0 4px 12px rgba(0,0,0,0.1);
}

.survival-effects h4 {
    color: var(--gray-600);
    margin-bottom: 2rem;
    display: flex;
    align-items: center;
    gap: 0.5rem;
}

.survival-measure-card {
    border: 2px solid #20c997;
    background: linear-gradient(135deg, #f0fff8, #d1ecf1);
    border-radius: 12px;
    padding: 2rem;
}

.survival-header {
    text-align: center;
    margin-bottom: 2rem;
    padding-bottom: 1rem;
    border-bottom: 2px solid rgba(0,0,0,0.1);
}

.survival-header h5 {
    color: var(--gray-600);
    margin-bottom: 0.5rem;
    font-size: 1.3rem;
}

.survival-formula {
    font-family: 'Times New Roman', serif;
    font-size: 1.2rem;
    font-weight: bold;
    background: white;
    padding: 0.75rem 1.5rem;
    border-radius: 8px;
    display: inline-block;
    box-shadow: 0 2px 4px rgba(0,0,0,0.1);
}

.survival-details {
    display: grid;
    grid-template-columns: 2fr 1fr;
    gap: 2rem;
}

.survival-properties, .survival-interpretation {
    background: white;
    padding: 1.5rem;
    border-radius: 8px;
    box-shadow: 0 2px 8px rgba(0,0,0,0.05);
}

.survival-properties h6, .survival-interpretation h6 {
    color: var(--gray-600);
    margin-bottom: 1rem;
}

.survival-properties ul {
    list-style: none;
    padding: 0;
}

.survival-properties li {
    position: relative;
    padding-left: 1.2rem;
    margin-bottom: 1rem;
    color: var(--gray-600);
    font-size: 0.9rem;
    line-height: 1.5;
}

.survival-properties li::before {
    content: "▸";
    position: absolute;
    left: 0;
    color: #20c997;
    font-weight: bold;
}

.hr-examples {
    display: flex;
    flex-direction: column;
    gap: 1rem;
}

.hr-example {
    display: flex;
    justify-content: space-between;
    align-items: center;
    padding: 1rem;
    background: var(--gray-50);
    border-radius: 8px;
    border: 1px solid var(--gray-200);
}

.hr-value {
    font-weight: bold;
    color: var(--gray-600);
}

.hr-meaning {
    color: var(--gray-500);
    font-size: 0.9rem;
}

/* Conversion Guide */
.conversion-guide {
    background: white;
    border-radius: 12px;
    padding: 2rem;
    box-shadow: 0 4px 12px rgba(0,0,0,0.1);
}

.conversion-guide h4 {
    color: var(--gray-600);
    margin-bottom: 2rem;
    display: flex;
    align-items: center;
    gap: 0.5rem;
}

.conversion-scenarios {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(300px, 1fr));
    gap: 2rem;
}

.scenario-card {
    background: var(--gray-50);
    border: 2px solid var(--gray-200);
    border-radius: 12px;
    padding: 2rem;
    text-align: center;
    transition: transform 0.3s ease, box-shadow 0.3s ease;
}

.scenario-card:hover {
    transform: translateY(-3px);
    box-shadow: 0 6px 20px rgba(0,0,0,0.1);
    border-color: var(--primary-600);
}

.scenario-card h5 {
    color: var(--gray-600);
    margin-bottom: 1rem;
    font-size: 1.1rem;
}

.conversion-formula {
    background: var(--gray-600);
    color: white;
    padding: 1rem;
    border-radius: 8px;
    margin: 1rem 0;
    font-family: 'Courier New', monospace;
}

.conversion-formula code {
    background: none;
    color: white;
    font-size: 1rem;
}

.scenario-card p {
    color: var(--gray-500);
    font-size: 0.9rem;
    line-height: 1.5;
    margin: 0;
}

/* ========================================
   GRADE 證據品質評估樣式
   ======================================== */

.grade-content {
    display: flex;
    flex-direction: column;
    gap: 3rem;
}

.grade-section {
    background: white;
    border-radius: 12px;
    padding: 2rem;
    box-shadow: 0 4px 12px rgba(0,0,0,0.1);
    border: 1px solid var(--gray-200);
}

.grade-section h3 {
    display: flex;
    align-items: center;
    gap: 0.75rem;
    color: var(--gray-700);
    margin-bottom: 1.5rem;
    padding-bottom: 1rem;
    border-bottom: 2px solid var(--gray-200);
}

.grade-section h3 i {
    color: var(--primary-600);
}

/* GRADE Introduction */
.grade-intro .intro-card {
    background: linear-gradient(135deg, #f0fdfa, #e0f7fa);
    border: 1px solid var(--primary-200);
}

/* Outcome Importance Section */
.outcome-importance {
    display: flex;
    flex-direction: column;
    gap: 2rem;
}

.outcome-intro {
    background: linear-gradient(135deg, #e8f4fd, #d1e9ff);
    padding: 1.25rem 1.5rem;
    border-radius: 10px;
    border-left: 4px solid #007bff;
}

.outcome-intro p {
    margin: 0;
    color: var(--gray-700);
    line-height: 1.6;
}

/* Rating Scale Section */
.rating-scale-section h4,
.patient-outcomes-section h4,
.surrogate-outcomes-section h4,
.rating-process-section h4 {
    display: flex;
    align-items: center;
    gap: 0.5rem;
    color: var(--gray-700);
    margin-bottom: 1rem;
    font-size: 1.1rem;
}

.rating-scale-section h4 i,
.patient-outcomes-section h4 i,
.surrogate-outcomes-section h4 i,
.rating-process-section h4 i {
    color: var(--primary-600);
}

.rating-scale-section > p {
    margin-bottom: 1.25rem;
    color: var(--gray-600);
}

/* Importance Scale Cards */
.importance-scale {
    display: flex;
    flex-direction: column;
    gap: 1rem;
}

.scale-category {
    border-radius: 12px;
    overflow: hidden;
    border: 2px solid;
}

.scale-category.critical {
    border-color: #dc3545;
}

.scale-category.important {
    border-color: #ffc107;
}

.scale-category.limited {
    border-color: #6c757d;
}

.scale-header {
    padding: 0.75rem 1.25rem;
    display: flex;
    align-items: center;
    gap: 1rem;
}

.scale-category.critical .scale-header {
    background: linear-gradient(135deg, #dc3545, #c82333);
    color: white;
}

.scale-category.important .scale-header {
    background: linear-gradient(135deg, #ffc107, #e0a800);
    color: #333;
}

.scale-category.limited .scale-header {
    background: linear-gradient(135deg, #6c757d, #5a6268);
    color: white;
}

.scale-range {
    font-weight: bold;
    font-size: 1.1rem;
    padding: 0.25rem 0.75rem;
    background: rgba(255,255,255,0.2);
    border-radius: 6px;
}

.scale-label {
    font-weight: 600;
    font-size: 1rem;
}

.scale-content {
    padding: 1.25rem;
    background: white;
}

.scale-content h5 {
    margin: 0 0 0.5rem 0;
    color: var(--gray-700);
    font-size: 0.95rem;
}

.scale-content > p {
    margin: 0;
    color: var(--gray-600);
    font-size: 0.9rem;
    line-height: 1.5;
}

.scale-note {
    margin-top: 1rem;
    padding: 0.75rem 1rem;
    background: #fff3cd;
    border-radius: 8px;
    display: flex;
    align-items: flex-start;
    gap: 0.75rem;
    font-size: 0.85rem;
    color: #856404;
}

.scale-note i {
    margin-top: 2px;
    color: #d39e00;
}

/* Patient Outcomes Grid */
.outcomes-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));
    gap: 1.5rem;
    margin-bottom: 1rem;
}

.outcome-type {
    border-radius: 12px;
    padding: 1.5rem;
    display: flex;
    gap: 1rem;
    align-items: flex-start;
}

.outcome-type.desired {
    background: linear-gradient(135deg, #d4edda, #c3e6cb);
    border: 1px solid #28a745;
}

.outcome-type.undesired {
    background: linear-gradient(135deg, #f8d7da, #f5c6cb);
    border: 1px solid #dc3545;
}

.outcome-icon {
    width: 48px;
    height: 48px;
    border-radius: 50%;
    display: flex;
    align-items: center;
    justify-content: center;
    flex-shrink: 0;
}

.outcome-type.desired .outcome-icon {
    background: #28a745;
    color: white;
    font-size: 1.5rem;
}

.outcome-type.undesired .outcome-icon {
    background: #dc3545;
    color: white;
    font-size: 1.5rem;
}

.outcome-content h5 {
    margin: 0 0 0.75rem 0;
    font-size: 1rem;
}

.outcome-type.desired .outcome-content h5 {
    color: #155724;
}

.outcome-type.undesired .outcome-content h5 {
    color: #721c24;
}

.outcome-content ul {
    margin: 0;
    padding-left: 1.25rem;
}

.outcome-content li {
    margin-bottom: 0.35rem;
    font-size: 0.9rem;
}

.outcome-type.desired .outcome-content li {
    color: #155724;
}

.outcome-type.undesired .outcome-content li {
    color: #721c24;
}

.outcome-tip {
    background: #e7f3ff;
    border-radius: 8px;
    padding: 1rem 1.25rem;
    display: flex;
    align-items: flex-start;
    gap: 0.75rem;
    font-size: 0.9rem;
    color: #004085;
    border-left: 3px solid #007bff;
}

.outcome-tip i {
    color: #007bff;
    margin-top: 2px;
}

/* Surrogate Outcomes */
.surrogate-comparison {
    display: grid;
    grid-template-columns: 1fr auto 1fr;
    gap: 1rem;
    align-items: stretch;
    margin-bottom: 1.25rem;
}

.surrogate-item {
    background: white;
    border-radius: 12px;
    padding: 1.5rem;
    border: 2px solid;
    position: relative;
}

.surrogate-item.clinical {
    border-color: #28a745;
}

.surrogate-item.surrogate {
    border-color: #ffc107;
}

.surrogate-item h5 {
    display: flex;
    align-items: center;
    gap: 0.5rem;
    margin: 0 0 0.5rem 0;
    font-size: 1rem;
}

.surrogate-item.clinical h5 {
    color: #28a745;
}

.surrogate-item.surrogate h5 {
    color: #d39e00;
}

.surrogate-item > p {
    margin: 0 0 1rem 0;
    color: var(--gray-600);
    font-size: 0.9rem;
}

.example-box {
    background: var(--gray-50);
    padding: 1rem;
    border-radius: 8px;
    margin-bottom: 1rem;
}

.example-box strong {
    display: block;
    margin-bottom: 0.5rem;
    color: var(--gray-700);
    font-size: 0.85rem;
}

.example-box ul {
    margin: 0;
    padding-left: 1.25rem;
}

.example-box li {
    font-size: 0.85rem;
    color: var(--gray-600);
    margin-bottom: 0.25rem;
}

.preference-badge {
    display: inline-block;
    padding: 0.35rem 0.75rem;
    border-radius: 20px;
    font-size: 0.8rem;
    font-weight: 600;
}

.preference-badge.preferred {
    background: #d4edda;
    color: #155724;
}

.preference-badge.caution {
    background: #fff3cd;
    color: #856404;
}

.surrogate-arrow {
    display: flex;
    align-items: center;
    justify-content: center;
    color: var(--gray-400);
    font-size: 1.5rem;
}

.surrogate-warning {
    background: #fff3cd;
    border-radius: 10px;
    padding: 1rem 1.25rem;
    display: flex;
    align-items: flex-start;
    gap: 1rem;
    border: 1px solid #ffc107;
}

.surrogate-warning > i {
    color: #d39e00;
    font-size: 1.25rem;
    margin-top: 2px;
}

.surrogate-warning strong {
    display: block;
    margin-bottom: 0.35rem;
    color: #856404;
}

.surrogate-warning p {
    margin: 0;
    color: #856404;
    font-size: 0.9rem;
    line-height: 1.5;
}

/* Rating Process Steps */
.process-steps {
    display: flex;
    flex-direction: column;
    gap: 1rem;
}

.process-step {
    display: flex;
    gap: 1rem;
    align-items: flex-start;
    background: var(--gray-50);
    padding: 1.25rem;
    border-radius: 10px;
    border: 1px solid var(--gray-200);
}

.process-number {
    width: 32px;
    height: 32px;
    border-radius: 50%;
    background: var(--primary-600);
    color: white;
    display: flex;
    align-items: center;
    justify-content: center;
    font-weight: bold;
    font-size: 0.9rem;
    flex-shrink: 0;
}

.process-content strong {
    display: block;
    margin-bottom: 0.35rem;
    color: var(--gray-700);
}

.process-content p {
    margin: 0;
    color: var(--gray-600);
    font-size: 0.9rem;
    line-height: 1.5;
}

/* Responsive for Outcome Importance */
@media (max-width: 768px) {
    .surrogate-comparison {
        grid-template-columns: 1fr;
    }

    .surrogate-arrow {
        transform: rotate(90deg);
        padding: 0.5rem 0;
    }

    .outcomes-grid {
        grid-template-columns: 1fr;
    }

    .process-step {
        flex-direction: column;
    }
}

/* Evidence Levels */
.evidence-levels {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));
    gap: 1.5rem;
}

.level-card {
    border-radius: 12px;
    overflow: hidden;
    border: 2px solid;
    transition: transform 0.3s ease, box-shadow 0.3s ease;
}

.level-card:hover {
    transform: translateY(-5px);
    box-shadow: 0 8px 24px rgba(0,0,0,0.15);
}

.level-header {
    padding: 1rem 1.5rem;
    display: flex;
    justify-content: space-between;
    align-items: center;
}

.level-icon {
    display: flex;
    gap: 0.25rem;
}

.level-icon i {
    font-size: 0.9rem;
}

.level-badge {
    font-size: 1.1rem;
    font-weight: bold;
    letter-spacing: 1px;
}

.level-content {
    padding: 1.5rem;
    background: white;
}

.level-content h4 {
    margin-bottom: 0.75rem;
    font-size: 1.15rem;
}

.level-meaning {
    font-weight: 500;
    margin-bottom: 1rem;
    line-height: 1.5;
}

.level-implication {
    font-size: 0.9rem;
    color: var(--gray-600);
    margin-bottom: 0.75rem;
}

.level-start {
    font-size: 0.85rem;
    color: var(--gray-500);
    padding-top: 0.75rem;
    border-top: 1px dashed var(--gray-300);
}

/* Level Colors */
.level-card.level-high {
    border-color: #28a745;
}
.level-card.level-high .level-header {
    background: linear-gradient(135deg, #28a745, #20c997);
    color: white;
}
.level-card.level-high .level-content h4 {
    color: #28a745;
}

.level-card.level-moderate {
    border-color: #17a2b8;
}
.level-card.level-moderate .level-header {
    background: linear-gradient(135deg, #17a2b8, #20c997);
    color: white;
}
.level-card.level-moderate .level-content h4 {
    color: #17a2b8;
}

.level-card.level-low {
    border-color: #ffc107;
}
.level-card.level-low .level-header {
    background: linear-gradient(135deg, #ffc107, #fd7e14);
    color: #333;
}
.level-card.level-low .level-content h4 {
    color: #d39e00;
}

.level-card.level-very-low {
    border-color: #dc3545;
}
.level-card.level-very-low .level-header {
    background: linear-gradient(135deg, #dc3545, #e83e8c);
    color: white;
}
.level-card.level-very-low .level-content h4 {
    color: #dc3545;
}

/* GRADE Flow */
.grade-flow {
    display: flex;
    flex-direction: column;
    align-items: center;
    gap: 0.5rem;
}

.flow-step {
    display: flex;
    gap: 1.5rem;
    align-items: flex-start;
    background: var(--gray-50);
    padding: 1.5rem;
    border-radius: 12px;
    width: 100%;
    max-width: 600px;
    border: 1px solid var(--gray-200);
}

.flow-step.final {
    background: linear-gradient(135deg, var(--primary-50), var(--primary-100));
    border-color: var(--primary-300);
}

.step-number {
    width: 40px;
    height: 40px;
    border-radius: 50%;
    background: var(--primary-600);
    color: white;
    display: flex;
    align-items: center;
    justify-content: center;
    font-weight: bold;
    font-size: 1.2rem;
    flex-shrink: 0;
}

.step-content h4 {
    margin-bottom: 0.5rem;
    color: var(--gray-700);
}

.step-content p {
    margin-bottom: 0.5rem;
    color: var(--gray-600);
    font-size: 0.9rem;
}

.step-content ul {
    margin: 0;
    padding-left: 1.25rem;
}

.step-content li {
    font-size: 0.9rem;
    color: var(--gray-600);
    margin-bottom: 0.25rem;
}

.flow-arrow {
    color: var(--primary-400);
    font-size: 1.5rem;
}

/* Factor Cards */
.downgrade-factors,
.upgrade-factors {
    display: flex;
    flex-direction: column;
    gap: 1.5rem;
}

.upgrade-intro {
    background: linear-gradient(135deg, #d4edda, #c3e6cb);
    padding: 1rem 1.5rem;
    border-radius: 8px;
    margin-bottom: 1rem;
    border-left: 4px solid #28a745;
}

.upgrade-intro p {
    margin: 0;
    color: #155724;
    display: flex;
    align-items: flex-start;
    gap: 0.75rem;
}

.factor-card {
    border-radius: 12px;
    overflow: hidden;
    border: 2px solid;
}

.factor-card.downgrade {
    border-color: #dc3545;
}

.factor-card.upgrade {
    border-color: #28a745;
}

.factor-header {
    display: flex;
    align-items: center;
    gap: 1rem;
    padding: 1.25rem 1.5rem;
}

.factor-card.downgrade .factor-header {
    background: linear-gradient(135deg, #f8d7da, #f5c6cb);
}

.factor-card.upgrade .factor-header {
    background: linear-gradient(135deg, #d4edda, #c3e6cb);
}

.factor-number {
    width: 36px;
    height: 36px;
    border-radius: 50%;
    background: #dc3545;
    color: white;
    display: flex;
    align-items: center;
    justify-content: center;
    font-weight: bold;
    font-size: 1.1rem;
    flex-shrink: 0;
}

.factor-number.up {
    background: #28a745;
}

.factor-title h4 {
    margin: 0 0 0.25rem 0;
    color: var(--gray-800);
    font-size: 1.1rem;
}

.factor-subtitle {
    margin: 0;
    color: var(--gray-600);
    font-size: 0.9rem;
}

.factor-body {
    padding: 1.5rem;
    background: white;
}

.factor-definition {
    background: var(--gray-50);
    padding: 1rem;
    border-radius: 8px;
    margin-bottom: 1.25rem;
    border-left: 3px solid var(--primary-500);
}

.factor-assess {
    margin-bottom: 1.25rem;
}

.factor-assess > strong {
    display: block;
    margin-bottom: 0.75rem;
    color: var(--gray-700);
}

.factor-assess ul {
    margin: 0;
    padding-left: 1.25rem;
}

.factor-assess li {
    margin-bottom: 0.5rem;
    line-height: 1.5;
    color: var(--gray-600);
}

.factor-criteria {
    display: flex;
    flex-direction: column;
    gap: 0.75rem;
    margin-bottom: 1rem;
}

.criteria-item {
    display: flex;
    align-items: center;
    gap: 1rem;
    padding: 0.75rem 1rem;
    border-radius: 8px;
}

.criteria-item.serious {
    background: #fff3cd;
    border: 1px solid #ffc107;
}

.criteria-item.very-serious {
    background: #f8d7da;
    border: 1px solid #dc3545;
}

.criteria-label {
    font-weight: 600;
    white-space: nowrap;
    padding: 0.25rem 0.75rem;
    border-radius: 4px;
    font-size: 0.85rem;
}

.criteria-item.serious .criteria-label {
    background: #ffc107;
    color: #333;
}

.criteria-item.very-serious .criteria-label {
    background: #dc3545;
    color: white;
}

.criteria-desc {
    color: var(--gray-700);
    font-size: 0.9rem;
}

.factor-tip {
    background: #e7f3ff;
    border-radius: 8px;
    padding: 0.75rem 1rem;
    display: flex;
    align-items: flex-start;
    gap: 0.75rem;
    font-size: 0.85rem;
    color: #0056b3;
    border-left: 3px solid #007bff;
}

.factor-tip i {
    margin-top: 2px;
}

.factor-requirements {
    margin-top: 1rem;
}

.factor-requirements > strong {
    display: block;
    margin-bottom: 0.5rem;
    color: var(--gray-700);
}

.factor-requirements ul {
    margin: 0;
    padding-left: 1.25rem;
}

.factor-requirements li {
    margin-bottom: 0.35rem;
    color: var(--gray-600);
    font-size: 0.9rem;
}

/* Effect Size Criteria */
.effect-size-criteria {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(200px, 1fr));
    gap: 1rem;
    margin-top: 0.75rem;
}

.effect-item {
    background: #d4edda;
    border-radius: 8px;
    padding: 1rem;
    text-align: center;
    border: 1px solid #28a745;
}

.effect-label {
    font-weight: 600;
    color: #155724;
    margin-bottom: 0.5rem;
}

.effect-value {
    font-size: 1.25rem;
    font-weight: bold;
    color: #28a745;
    margin-bottom: 0.5rem;
    font-family: 'JetBrains Mono', monospace;
}

.effect-desc {
    font-size: 0.85rem;
    color: #155724;
}

/* GRADE Reference Table */
.grade-table-container {
    overflow-x: auto;
}

.grade-reference-table {
    width: 100%;
    border-collapse: collapse;
    font-size: 0.9rem;
}

.grade-reference-table th,
.grade-reference-table td {
    padding: 0.75rem 1rem;
    text-align: left;
    border: 1px solid var(--gray-300);
}

.grade-reference-table th {
    background: var(--gray-700);
    color: white;
    font-weight: 600;
}

.grade-reference-table .downgrade-row {
    background: #fff5f5;
}

.grade-reference-table .upgrade-row {
    background: #f0fff4;
}

.grade-reference-table tr:hover {
    background: var(--gray-100);
}

.grade-reference-table .downgrade-row:hover {
    background: #ffe5e5;
}

.grade-reference-table .upgrade-row:hover {
    background: #e0ffe5;
}

/* GRADE Resources */
.grade-resources {
    display: flex;
    flex-direction: column;
    gap: 0.75rem;
}

.grade-resources .resource-link {
    display: flex;
    align-items: center;
    gap: 0.75rem;
    padding: 1rem 1.25rem;
    background: var(--gray-50);
    border-radius: 8px;
    border: 1px solid var(--gray-200);
    text-decoration: none;
    color: var(--primary-700);
    font-weight: 500;
    transition: all 0.3s ease;
}

.grade-resources .resource-link:hover {
    background: var(--primary-50);
    border-color: var(--primary-300);
    transform: translateX(5px);
}

.grade-resources .resource-link i {
    font-size: 1.25rem;
    color: var(--primary-500);
    min-width: 24px;
}

/* Responsive adjustments for GRADE */
@media (max-width: 768px) {
    .evidence-levels {
        grid-template-columns: 1fr;
    }

    .flow-step {
        flex-direction: column;
        gap: 1rem;
    }

    .step-number {
        align-self: flex-start;
    }

    .effect-size-criteria {
        grid-template-columns: 1fr;
    }

    .criteria-item {
        flex-direction: column;
        align-items: flex-start;
        gap: 0.5rem;
    }

    .grade-reference-table {
        font-size: 0.8rem;
    }

    .grade-reference-table th,
    .grade-reference-table td {
        padding: 0.5rem;
    }
}

/* Risk of Bias 2.0 Styles */
.rob-content {
    display: flex;
    flex-direction: column;
    gap: 3rem;
}

.rob-section {
    background: white;
    border-radius: 12px;
    padding: 2rem;
    box-shadow: 0 4px 12px rgba(0,0,0,0.1);
    border: 1px solid var(--gray-200);
}

.rob-section h3 {
    color: var(--gray-600);
    margin-bottom: 2rem;
    display: flex;
    align-items: center;
    gap: 0.5rem;
    font-size: 1.3rem;
}

/* RoB Introduction */
.rob-intro {
    display: flex;
    flex-direction: column;
    gap: 2rem;
}

.intro-card {
    background: white;
    border-radius: 12px;
    color: var(--gray-800);
    padding: 2rem;
    box-shadow: 0 4px 12px rgba(0, 0, 0, 0.1);
    border: 1px solid var(--gray-200);
}

.intro-content p {
    font-size: 1.1rem;
    line-height: 1.6;
    margin-bottom: 2rem;
}

.intro-highlights {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(250px, 1fr));
    gap: 1.5rem;
}

.highlight-item {
    display: flex;
    align-items: flex-start;
    gap: 1rem;
    background: var(--gray-50);
    padding: 1.5rem;
    border-radius: 8px;
    border: 1px solid var(--gray-200);
}

.highlight-item i {
    font-size: 2rem;
    color: var(--primary-600);
    min-width: 40px;
}

.highlight-item strong {
    display: block;
    margin-bottom: 0.5rem;
    font-size: 1.1rem;
}

.highlight-item p {
    margin: 0;
    font-size: 0.9rem;
    opacity: 0.9;
}

/* Domains Overview */
.domains-overview {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(300px, 1fr));
    gap: 2rem;
}

.domain-card {
    border-radius: 12px;
    padding: 2rem;
    border: 2px solid;
    transition: transform 0.3s ease, box-shadow 0.3s ease;
    display: flex;
    gap: 1.5rem;
}

.domain-card:hover {
    transform: translateY(-5px);
    box-shadow: 0 8px 24px rgba(0,0,0,0.15);
}

.domain-card.domain-1 {
    border-color: #007bff;
    background: linear-gradient(135deg, #f0f8ff, #cce5ff);
}

.domain-card.domain-2 {
    border-color: var(--success);
    background: linear-gradient(135deg, #f0fff4, #d4edda);
}

.domain-card.domain-3 {
    border-color: var(--warning);
    background: linear-gradient(135deg, #fffbf0, #fff3cd);
}

.domain-card.domain-4 {
    border-color: #fd7e14;
    background: linear-gradient(135deg, #fff8f0, #ffe4cc);
}

.domain-card.domain-5 {
    border-color: #e83e8c;
    background: linear-gradient(135deg, #fff0f6, #f8d7da);
}

.domain-icon {
    font-size: 3rem;
    color: var(--gray-600);
    min-width: 60px;
    text-align: center;
    display: flex;
    align-items: center;
    justify-content: center;
}

.domain-content h4 {
    color: var(--gray-600);
    margin-bottom: 0.5rem;
    font-size: 1.2rem;
}

.domain-content p {
    color: var(--gray-500);
    font-style: italic;
    margin-bottom: 1rem;
    font-size: 0.9rem;
}

.domain-content ul {
    list-style: none;
    padding: 0;
    margin: 0;
}

.domain-content li {
    position: relative;
    padding-left: 1.2rem;
    margin-bottom: 0.5rem;
    color: var(--gray-600);
    font-size: 0.9rem;
}

.domain-content li::before {
    content: "▸";
    position: absolute;
    left: 0;
    color: var(--primary-600);
    font-weight: bold;
}

/* Domain Number Badge */
.domain-number {
    position: absolute;
    top: -10px;
    right: -10px;
    background: var(--gray-700);
    color: white;
    width: 36px;
    height: 36px;
    border-radius: 50%;
    display: flex;
    align-items: center;
    justify-content: center;
    font-weight: bold;
    font-size: 0.9rem;
    box-shadow: 0 2px 8px rgba(0,0,0,0.2);
}

.domain-card {
    position: relative;
}

.domain-card.domain-1 .domain-number { background: #007bff; }
.domain-card.domain-2 .domain-number { background: var(--success); }
.domain-card.domain-3 .domain-number { background: var(--warning); color: var(--gray-800); }
.domain-card.domain-4 .domain-number { background: #fd7e14; }
.domain-card.domain-5 .domain-number { background: #e83e8c; }

.domain-en {
    color: var(--gray-500);
    font-style: italic;
    font-size: 0.85rem;
    margin-bottom: 1rem;
}

.domain-description {
    margin-bottom: 1rem;
}

.domain-description p {
    font-style: normal;
    color: var(--gray-700);
    margin-bottom: 0.75rem;
}

.domain-description ul {
    margin-top: 0.5rem;
}

.domain-description li {
    margin-bottom: 0.75rem;
    line-height: 1.5;
}

.domain-tip {
    background: rgba(255, 255, 255, 0.7);
    border-radius: 8px;
    padding: 0.75rem 1rem;
    display: flex;
    align-items: flex-start;
    gap: 0.75rem;
    font-size: 0.85rem;
    color: var(--gray-600);
    border-left: 3px solid var(--primary-500);
}

.domain-tip i {
    color: var(--warning);
    font-size: 1rem;
    margin-top: 2px;
}

/* Judgment Criteria Card */
.judgment-criteria h4,
.effect-types h4,
.resources h4 {
    display: flex;
    align-items: center;
    gap: 0.75rem;
    margin-bottom: 1.5rem;
    color: var(--gray-700);
    font-size: 1.15rem;
}

.judgment-levels {
    display: flex;
    flex-direction: column;
    gap: 1rem;
}

.judgment-item {
    display: flex;
    align-items: flex-start;
    gap: 1rem;
    padding: 1.25rem;
    border-radius: 10px;
    border: 1px solid;
}

.judgment-item.low-risk {
    background: linear-gradient(135deg, #d4edda, #c3e6cb);
    border-color: #28a745;
}

.judgment-item.some-concerns {
    background: linear-gradient(135deg, #fff3cd, #ffeeba);
    border-color: #ffc107;
}

.judgment-item.high-risk {
    background: linear-gradient(135deg, #f8d7da, #f5c6cb);
    border-color: #dc3545;
}

.judgment-icon {
    font-size: 1.75rem;
    min-width: 40px;
}

.judgment-item.low-risk .judgment-icon { color: #28a745; }
.judgment-item.some-concerns .judgment-icon { color: #856404; }
.judgment-item.high-risk .judgment-icon { color: #dc3545; }

.judgment-content strong {
    display: block;
    margin-bottom: 0.5rem;
    font-size: 1.05rem;
}

.judgment-content p {
    margin: 0;
    font-size: 0.9rem;
    line-height: 1.5;
    color: var(--gray-700);
}

/* Effect Types Card */
.effect-types > p {
    margin-bottom: 1rem;
    color: var(--gray-600);
}

.effect-type-options {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));
    gap: 1rem;
}

.effect-type-item {
    background: var(--gray-50);
    padding: 1.25rem;
    border-radius: 10px;
    border: 1px solid var(--gray-200);
}

.effect-type-item strong {
    display: flex;
    align-items: center;
    gap: 0.5rem;
    margin-bottom: 0.75rem;
    color: var(--primary-700);
}

.effect-type-item p {
    margin: 0;
    font-size: 0.9rem;
    color: var(--gray-600);
    line-height: 1.5;
}

/* Resources Card */
.resource-links {
    display: flex;
    flex-direction: column;
    gap: 0.75rem;
}

.resource-link {
    display: flex;
    align-items: center;
    gap: 0.75rem;
    padding: 1rem 1.25rem;
    background: var(--gray-50);
    border-radius: 8px;
    border: 1px solid var(--gray-200);
    text-decoration: none;
    color: var(--primary-700);
    font-weight: 500;
    transition: all 0.3s ease;
}

.resource-link:hover {
    background: var(--primary-50);
    border-color: var(--primary-300);
    transform: translateX(5px);
}

.resource-link i {
    font-size: 1.25rem;
    color: var(--primary-500);
    min-width: 24px;
}

/* Study Management */
.study-management {
    display: flex;
    flex-direction: column;
    gap: 2rem;
}

.management-controls {
    display: flex;
    gap: 1rem;
    flex-wrap: wrap;
}

.rob-btn {
    padding: 0.75rem 1.5rem;
    border: none;
    border-radius: 8px;
    font-weight: 600;
    cursor: pointer;
    transition: all 0.3s ease;
    display: flex;
    align-items: center;
    gap: 0.5rem;
    text-decoration: none;
    font-size: 0.9rem;
}

.rob-btn:hover {
    transform: translateY(-2px);
    box-shadow: 0 4px 12px rgba(0,0,0,0.15);
}

.rob-btn.primary {
    background: #007bff;
    color: white;
}

.rob-btn.primary:hover {
    background: #0056b3;
}

.rob-btn.secondary {
    background: var(--gray-500);
    color: white;
}

.rob-btn.secondary:hover {
    background: #545b62;
}

.rob-btn.info {
    background: var(--info);
    color: white;
}

.rob-btn.info:hover {
    background: #117a8b;
}

.rob-btn.success {
    background: var(--success);
    color: white;
}

.rob-btn.success:hover {
    background: #1e7e34;
}

.rob-btn.danger {
    background: #dc3545;
    color: white;
}

.rob-btn.danger:hover {
    background: #c82333;
}

.studies-container {
    background: var(--gray-50);
    border-radius: 12px;
    padding: 2rem;
    min-height: 200px;
    border: 2px dashed var(--gray-200);
}

.empty-state {
    text-align: center;
    color: var(--gray-500);
    padding: 3rem;
}

.empty-state i {
    font-size: 4rem;
    margin-bottom: 1rem;
    color: var(--gray-200);
}

.empty-state h4 {
    margin-bottom: 0.5rem;
    color: var(--gray-600);
}

/* Assessment Container */
.assessment-container {
    display: flex;
    flex-direction: column;
    gap: 2rem;
}

.assessment-header {
    background: var(--gray-50);
    padding: 1.5rem;
    border-radius: 8px;
    border: 1px solid var(--gray-200);
}

.progress-bar {
    background: var(--gray-200);
    height: 8px;
    border-radius: 4px;
    overflow: hidden;
    margin-top: 1rem;
}

.progress-fill {
    background: linear-gradient(90deg, #007bff, var(--success));
    height: 100%;
    width: 0%;
    transition: width 0.3s ease;
}

.overall-risk {
    background: var(--gray-50);
    padding: 2rem;
    border-radius: 12px;
    border: 1px solid var(--gray-200);
}

.overall-risk h4 {
    color: var(--gray-600);
    margin-bottom: 1.5rem;
    display: flex;
    align-items: center;
    gap: 0.5rem;
}

.assessment-controls {
    display: flex;
    gap: 1rem;
    justify-content: center;
    flex-wrap: wrap;
    padding: 2rem 0;
    border-top: 1px solid var(--gray-200);
}

/* Visualization Controls */
.visualization-controls {
    display: flex;
    justify-content: space-between;
    align-items: center;
    margin-bottom: 2rem;
    flex-wrap: wrap;
    gap: 1rem;
}

.chart-options, .export-options {
    display: flex;
    gap: 0.5rem;
    flex-wrap: wrap;
}

.chart-btn, .export-btn {
    padding: 0.5rem 1rem;
    border: 2px solid #007bff;
    background: white;
    color: #007bff;
    border-radius: 6px;
    cursor: pointer;
    transition: all 0.3s ease;
    font-size: 0.9rem;
    display: flex;
    align-items: center;
    gap: 0.5rem;
}

.chart-btn:hover, .export-btn:hover {
    background: #007bff;
    color: white;
    transform: translateY(-2px);
}

.chart-btn.active {
    background: #007bff;
    color: white;
}

.export-btn {
    border-color: var(--success);
    color: var(--success);
}

.export-btn:hover {
    background: var(--success);
    color: white;
}

.chart-container {
    background: var(--gray-50);
    border-radius: 12px;
    padding: 2rem;
    min-height: 400px;
    border: 1px solid var(--gray-200);
    position: relative;
}

.chart-placeholder {
    display: flex;
    flex-direction: column;
    align-items: center;
    justify-content: center;
    height: 400px;
    color: var(--gray-500);
}

.chart-placeholder i {
    font-size: 4rem;
    margin-bottom: 1rem;
    color: var(--gray-200);
}

/* Help Content */
.help-content {
    background: var(--gray-50);
    border-radius: 12px;
    padding: 2rem;
}

.help-accordion {
    display: flex;
    flex-direction: column;
    gap: 1rem;
}

.help-item {
    background: white;
    border-radius: 8px;
    border: 1px solid var(--gray-200);
    overflow: hidden;
}

.help-header {
    padding: 1rem 1.5rem;
    background: var(--gray-50);
    cursor: pointer;
    display: flex;
    justify-content: space-between;
    align-items: center;
    transition: background-color 0.3s ease;
}

.help-header:hover {
    background: var(--gray-200);
}

.help-header span {
    display: flex;
    align-items: center;
    gap: 0.5rem;
    font-weight: 600;
    color: var(--gray-600);
}

.help-content {
    padding: 1.5rem;
    display: none;
    background: white;
}

.help-content.active {
    display: block;
}

.help-content ol, .help-content ul {
    padding-left: 1.5rem;
}

.help-content li {
    margin-bottom: 0.5rem;
    line-height: 1.6;
    color: var(--gray-600);
}

/* Tips Container */
.tips-container {
    background: var(--gray-50);
    border-radius: 12px;
    padding: 2rem;
}

/* Help Tips Grid */
.help-tips-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));
    gap: 1.25rem;
}

.tip-card {
    background: white;
    border-radius: 12px;
    padding: 1.5rem;
    display: flex;
    gap: 1rem;
    align-items: flex-start;
    border: 1px solid var(--gray-200);
    transition: all 0.3s ease;
}

.tip-card:hover {
    border-color: var(--primary-400);
    box-shadow: 0 4px 12px rgba(13, 148, 136, 0.1);
    transform: translateY(-2px);
}

.tip-icon {
    width: 48px;
    height: 48px;
    border-radius: 12px;
    background: linear-gradient(135deg, var(--primary-100), var(--primary-200));
    display: flex;
    align-items: center;
    justify-content: center;
    flex-shrink: 0;
}

.tip-icon i {
    font-size: 1.25rem;
    color: var(--primary-600);
}

.tip-content strong {
    display: block;
    margin-bottom: 0.5rem;
    color: var(--gray-700);
    font-size: 1rem;
}

.tip-content p {
    margin: 0;
    font-size: 0.9rem;
    color: var(--gray-600);
    line-height: 1.5;
}

/* Study Item Styles */
.study-item {
    background: white;
    border-radius: 12px;
    border: 2px solid var(--gray-200);
    margin-bottom: 1rem;
    overflow: hidden;
    transition: all 0.3s ease;
}

.study-item:hover {
    border-color: var(--primary-600);
    box-shadow: 0 4px 16px rgba(13, 148, 136, 0.1);
}

.study-header {
    display: flex;
    justify-content: space-between;
    align-items: center;
    padding: 1.5rem;
    background: var(--gray-50);
}

.study-info h4 {
    color: var(--gray-600);
    margin-bottom: 0.5rem;
    font-size: 1.1rem;
}

.study-info p {
    color: var(--gray-500);
    margin: 0;
    font-size: 0.9rem;
}

.study-status {
    display: flex;
    align-items: center;
    gap: 1rem;
}

.progress-circle {
    width: 60px;
    height: 60px;
    border-radius: 50%;
    background: conic-gradient(var(--success) calc(var(--progress) * 1%), var(--gray-200) 0);
    display: flex;
    align-items: center;
    justify-content: center;
    position: relative;
}

.progress-circle::before {
    content: '';
    position: absolute;
    inset: 8px;
    border-radius: 50%;
    background: white;
}

.progress-circle span {
    position: relative;
    z-index: 1;
    font-weight: bold;
    font-size: 0.8rem;
    color: var(--gray-600);
}

.risk-badge {
    padding: 0.5rem 1rem;
    border-radius: 20px;
    font-size: 0.8rem;
    font-weight: 600;
    text-align: center;
}

.risk-badge.low-risk {
    background: #d4edda;
    color: #155724;
    border: 1px solid #c3e6cb;
}

.risk-badge.some-concerns {
    background: #fff3cd;
    color: #856404;
    border: 1px solid #ffeaa7;
}

.risk-badge.high-risk {
    background: #f8d7da;
    color: #721c24;
    border: 1px solid #f5c6cb;
}

.study-controls {
    display: flex;
    gap: 0.5rem;
    padding: 1rem 1.5rem;
    background: white;
    border-top: 1px solid var(--gray-200);
}

/* Assessment Form Styles */
.study-form {
    background: white;
    padding: 2rem;
    border-radius: 8px;
    border: 1px solid var(--gray-200);
}

.form-row {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(250px, 1fr));
    gap: 1rem;
    margin-bottom: 1rem;
}

.form-group {
    display: flex;
    flex-direction: column;
    gap: 0.5rem;
}

.form-group label {
    font-weight: 600;
    color: var(--gray-600);
}

.form-group input, .form-group textarea {
    padding: 0.75rem;
    border: 2px solid var(--gray-200);
    border-radius: 6px;
    font-size: 0.9rem;
    transition: border-color 0.3s ease;
}

.form-group input:focus, .form-group textarea:focus {
    outline: none;
    border-color: var(--primary-600);
}

/* Domain Assessment Styles */
.domain-assessment {
    background: white;
    border: 2px solid var(--gray-200);
    border-radius: 12px;
    margin-bottom: 2rem;
    overflow: hidden;
}

.domain-header {
    background: var(--gray-50);
    padding: 1.5rem;
    display: flex;
    justify-content: space-between;
    align-items: center;
    border-bottom: 1px solid var(--gray-200);
}

.domain-header h4 {
    color: var(--gray-600);
    margin: 0;
    font-size: 1.2rem;
}

.domain-judgment select {
    padding: 0.5rem 1rem;
    border: 2px solid var(--gray-200);
    border-radius: 6px;
    background: white;
    font-weight: 600;
    min-width: 120px;
}

.domain-judgment select:focus {
    outline: none;
    border-color: var(--primary-600);
}

.domain-questions {
    padding: 2rem;
}

.question-item {
    background: var(--gray-50);
    padding: 1.5rem;
    border-radius: 8px;
    margin-bottom: 1.5rem;
    border: 1px solid var(--gray-200);
}

.question-text {
    font-weight: 600;
    color: var(--gray-600);
    margin-bottom: 1rem;
    line-height: 1.5;
}

.answer-options {
    display: flex;
    gap: 1rem;
    flex-wrap: wrap;
}

.radio-option {
    display: flex;
    align-items: center;
    gap: 0.5rem;
    cursor: pointer;
    padding: 0.5rem 1rem;
    border-radius: 20px;
    background: white;
    border: 2px solid var(--gray-200);
    transition: all 0.3s ease;
}

.radio-option:hover {
    border-color: var(--primary-600);
    background: var(--primary-50);
}

.radio-option input[type="radio"] {
    display: none;
}

.radio-custom {
    width: 16px;
    height: 16px;
    border-radius: 50%;
    border: 2px solid var(--gray-200);
    position: relative;
}

.radio-option input[type="radio"]:checked + .radio-custom::after {
    content: '';
    position: absolute;
    top: 2px;
    left: 2px;
    width: 8px;
    height: 8px;
    border-radius: 50%;
    background: white;
}

.radio-option input[type="radio"]:checked + .radio-custom.yes {
    background: var(--success);
    border-color: var(--success);
}

.radio-option input[type="radio"]:checked + .radio-custom.probably-yes {
    background: #20c997;
    border-color: #20c997;
}

.radio-option input[type="radio"]:checked + .radio-custom.probably-no {
    background: var(--warning);
    border-color: var(--warning);
}

.radio-option input[type="radio"]:checked + .radio-custom.no {
    background: #dc3545;
    border-color: #dc3545;
}

.radio-option input[type="radio"]:checked + .radio-custom.no-info {
    background: var(--gray-500);
    border-color: var(--gray-500);
}

.domain-rationale {
    padding: 2rem;
    background: var(--gray-50);
    border-top: 1px solid var(--gray-200);
}

.domain-rationale label {
    font-weight: 600;
    color: var(--gray-600);
    display: block;
    margin-bottom: 0.5rem;
}

.domain-rationale textarea {
    width: 100%;
    min-height: 100px;
    padding: 1rem;
    border: 2px solid var(--gray-200);
    border-radius: 6px;
    font-family: inherit;
    resize: vertical;
}

.domain-rationale textarea:focus {
    outline: none;
    border-color: var(--primary-600);
}

/* Risk Result Styles */
.risk-result {
    display: flex;
    align-items: center;
    gap: 1.5rem;
    padding: 2rem;
    border-radius: 12px;
    border: 2px solid;
}

.risk-result.low-risk {
    background: linear-gradient(135deg, #d4edda, #c3e6cb);
    border-color: var(--success);
}

.risk-result.some-concerns {
    background: linear-gradient(135deg, #fff3cd, #ffeaa7);
    border-color: var(--warning);
}

.risk-result.high-risk {
    background: linear-gradient(135deg, #f8d7da, #f5c6cb);
    border-color: #dc3545;
}

.risk-icon {
    font-size: 3rem;
    color: var(--gray-600);
}

.risk-text h5 {
    color: var(--gray-600);
    margin-bottom: 0.5rem;
    font-size: 1.3rem;
}

.risk-text p {
    color: var(--gray-500);
    margin: 0;
    line-height: 1.5;
}

.text-muted {
    color: var(--gray-500);
    font-style: italic;
}

/* Chart styles for RoB */
#rob-chart {
    display: none;
    max-width: 100%;
    height: 400px;
}

.chart-container canvas {
    max-width: 100%;
}

/* Responsive adjustments for RoB */
@media (max-width: 768px) {
    .study-header {
        flex-direction: column;
        gap: 1rem;
        text-align: center;
    }
    
    .study-status {
        justify-content: center;
    }
    
    .study-controls {
        flex-wrap: wrap;
        justify-content: center;
    }
    
    .form-row {
        grid-template-columns: 1fr;
    }
    
    .answer-options {
        flex-direction: column;
        gap: 0.5rem;
    }
    
    .domain-header {
        flex-direction: column;
        gap: 1rem;
        text-align: center;
    }
    
    .risk-result {
        flex-direction: column;
        text-align: center;
    }
    
    .chart-options, .export-options {
        justify-content: center;
    }
    
    .visualization-controls {
        flex-direction: column;
        align-items: center;
    }
}

/* RoB 2.0 Cochrane Standard Table Styles */
.rob-table-container {
    background: white;
    border-radius: 8px;
    padding: 20px;
    box-shadow: 0 2px 10px rgba(0,0,0,0.1);
    margin: 20px 0;
    overflow-x: auto;
    min-width: 100%;
}

.rob-title {
    font-size: 14px;
    font-weight: bold;
    text-align: center;
    margin-bottom: 10px;
    color: #666;
}

.rob-table-container {
    background: white;
    border-radius: 8px;
    padding: 20px;
    box-shadow: 0 2px 10px rgba(0,0,0,0.1);
    margin: 20px 0;
}

.rob-table {
    width: 100%;
    border-collapse: collapse;
    border: 3px solid #333;
    font-family: Arial, sans-serif;
    table-layout: fixed;
    min-width: 600px;
}

/* Header row styling */
.rob-table thead tr {
    background-color: #d3d3d3;
}

.study-header-cell {
    background-color: #d3d3d3;
    border: 1px solid #333;
    padding: 8px 12px;
    font-weight: bold;
    font-size: 12px;
    text-align: center;
    vertical-align: middle;
    min-width: 120px;
}

.domain-header-cell {
    background-color: #d3d3d3;
    border: 1px solid #333;
    padding: 8px 8px;
    font-weight: bold;
    font-size: 12px;
    text-align: center;
    vertical-align: middle;
    min-width: 50px;
}

.overall-header-cell {
    background-color: #b8b8b8;
    border: 1px solid #333;
    padding: 8px 8px;
    font-weight: bold;
    font-size: 12px;
    text-align: center;
    vertical-align: middle;
    min-width: 70px;
}

/* Data rows styling */
.study-name-cell {
    background-color: #d3d3d3;
    border: 1px solid #333;
    padding: 8px 12px;
    font-weight: normal;
    font-size: 11px;
    text-align: left;
    vertical-align: middle;
    min-width: 120px;
}

.data-cell {
    background-color: white;
    border: 1px solid #333;
    padding: 6px;
    text-align: center;
    vertical-align: middle;
    min-width: 50px;
}

.overall-data-cell {
    background-color: #f0f0f0;
    border: 1px solid #333;
    padding: 6px;
    text-align: center;
    vertical-align: middle;
    min-width: 70px;
}

/* Risk circle styling */
.risk-circle {
    width: 28px;
    height: 28px;
    border-radius: 50%;
    display: flex;
    align-items: center;
    justify-content: center;
    font-weight: bold;
    font-size: 16px;
    margin: 0 auto;
    border: 2px solid #000;
}

.risk-circle.low-risk {
    background-color: #4CAF50;
    color: black;
    border-color: #333;
}

.risk-circle.some-concerns {
    background-color: #FFEB3B;
    color: black;
    border-color: #333;
}

.risk-circle.high-risk {
    background-color: #F44336;
    color: black;
    border-color: #333;
}

.risk-circle.no-information {
    background-color: #2196F3;
    color: black;
    border-color: #333;
}

.rob-legend {
    display: flex;
    gap: 40px;
    margin-top: 20px;
}

.legend-section {
    flex: 1;
}

.legend-section h4 {
    margin-bottom: 15px;
    font-size: 16px;
    font-weight: bold;
}

.legend-section p {
    margin-bottom: 8px;
    font-size: 14px;
    line-height: 1.4;
}

.legend-item {
    display: flex;
    align-items: center;
    gap: 10px;
    margin-bottom: 10px;
}

.legend-item .risk-circle {
    width: 20px;
    height: 20px;
    font-size: 12px;
    margin: 0;
}

.legend-item span {
    font-size: 14px;
}

/* Responsive adjustments for RoB table */
@media (max-width: 768px) {
    .rob-legend {
        flex-direction: column;
        gap: 20px;
    }
    
    .rob-table {
        font-size: 12px;
    }
    
    .rob-table th,
    .rob-table td {
        padding: 8px 4px;
    }
    
    .study-column {
        min-width: 150px;
    }
    
    .risk-circle {
        width: 25px;
        height: 25px;
        font-size: 14px;
    }
}

/* ==========================================
   COMPREHENSIVE MOBILE OPTIMIZATION
   ========================================== */

/* Mobile-first approach for better UX */
@media (max-width: 768px) {
    /* Global adjustments */
    body {
        font-size: 14px;
        line-height: 1.6;
    }
    
    .container {
        padding: 0 10px;
        max-width: 100%;
    }
    
    /* Header optimization */
    .header {
        padding: 1rem 0;
        position: sticky;
        top: 0;
        z-index: 1000;
        background: white;
        box-shadow: 0 2px 4px rgba(0,0,0,0.1);
    }
    
    .header h1 {
        font-size: 1.5rem;
        text-align: center;
    }
    
    .header p {
        font-size: 0.875rem;
    }
    
    /* Navigation tabs - horizontal scroll */
    .nav-tabs {
        display: flex;
        overflow-x: auto;
        -webkit-overflow-scrolling: touch;
        scrollbar-width: thin;
        padding: 0.5rem 0;
        gap: 0.5rem;
        margin: 0 -10px;
        padding-left: 10px;
        padding-right: 10px;
    }
    
    .nav-tab {
        flex: 0 0 auto;
        padding: 0.75rem 1rem;
        font-size: 0.875rem;
        white-space: nowrap;
        min-height: 44px; /* iOS touch target */
        display: flex;
        align-items: center;
        justify-content: center;
    }
    
    /* Buttons optimization */
    button, .btn, .rob-btn, .formula-btn {
        min-height: 44px;
        min-width: 44px;
        padding: 12px 16px;
        font-size: 14px;
        touch-action: manipulation;
    }
    
    /* Form elements */
    input[type="text"],
    input[type="number"],
    input[type="email"],
    input[type="tel"],
    select,
    textarea {
        min-height: 44px;
        padding: 10px 12px;
        font-size: 16px; /* Prevents zoom on iOS */
        width: 100%;
    }
    
    /* Stack form rows on mobile */
    .input-row,
    .form-row {
        grid-template-columns: 1fr;
        gap: 1rem;
    }
    
    .input-group {
        display: flex;
        flex-direction: column;
        gap: 0.5rem;
    }
    
    /* Module cards */
    .module-content {
        padding: 1rem;
    }
    
    .module-header h2 {
        font-size: 1.25rem;
    }
    
    /* RoB management controls */
    .management-controls {
        display: grid;
        grid-template-columns: 1fr 1fr;
        gap: 0.5rem;
        margin-bottom: 1rem;
    }
    
    .management-controls .rob-btn {
        font-size: 0.75rem;
        padding: 0.5rem;
    }
    
    .management-controls .rob-btn i {
        display: block;
        margin-bottom: 0.25rem;
    }
    
    /* Study items */
    .study-item {
        padding: 0.75rem;
        margin-bottom: 0.75rem;
    }
    
    .study-header {
        flex-direction: column;
        gap: 0.75rem;
    }
    
    .study-controls {
        display: grid;
        grid-template-columns: repeat(3, 1fr);
        gap: 0.5rem;
    }
    
    .study-controls .rob-btn {
        font-size: 0.75rem;
        padding: 0.5rem;
    }
    
    /* Tables - make them scrollable */
    .table-responsive {
        overflow-x: auto;
        -webkit-overflow-scrolling: touch;
        margin: 0 -1rem;
        padding: 0 1rem;
    }
    
    table {
        min-width: 600px;
    }
    
    .rob-table {
        display: block;
        overflow-x: auto;
        white-space: nowrap;
    }
    
    /* Charts and visualizations */
    canvas {
        max-width: 100%;
        height: auto !important;
    }
    
    #rob-chart {
        max-height: 300px;
    }
    
    /* Accordion sections */
    .accordion-header {
        padding: 1rem;
        font-size: 1rem;
    }
    
    .accordion-content {
        padding: 1rem;
    }
    
    /* Modal dialogs */
    .modal-content {
        width: 95%;
        max-width: 100%;
        margin: 10px;
        max-height: 90vh;
        overflow-y: auto;
    }
    
    /* Tab content sections */
    .tab-content {
        padding: 1rem;
    }
    
    /* Risk assessment domains */
    .domain-section {
        margin-bottom: 1.5rem;
        padding: 1rem;
    }
    
    .domain-header {
        font-size: 1rem;
        padding: 0.75rem;
    }
    
    .signalling-questions {
        padding: 0.75rem;
    }
    
    .question-group {
        margin-bottom: 1rem;
    }
    
    .answer-options {
        display: grid;
        grid-template-columns: repeat(2, 1fr);
        gap: 0.5rem;
    }
    
    .answer-options label {
        padding: 0.5rem;
        font-size: 0.875rem;
        text-align: center;
    }
    
    /* Export options */
    .export-options {
        display: grid;
        grid-template-columns: 1fr;
        gap: 0.5rem;
    }
    
    /* Help sections */
    .help-section {
        padding: 1rem;
    }
    
    .help-header {
        font-size: 1rem;
        padding: 0.75rem;
    }
    
    /* Formula cards */
    .formula-card {
        padding: 1rem;
        margin-bottom: 1rem;
    }
    
    .formula-content {
        font-size: 0.875rem;
    }
    
    /* Results display */
    .result-box {
        padding: 1rem;
        margin: 1rem 0;
    }
    
    .result-value {
        font-size: 1.25rem;
    }
    
    /* Footer adjustments */
    footer {
        padding: 1.5rem 0;
        font-size: 0.875rem;
    }
}

/* Small mobile screens (iPhone SE, etc.) */
@media (max-width: 375px) {
    .header h1 {
        font-size: 1.25rem;
    }
    
    .nav-tab {
        padding: 0.5rem 0.75rem;
        font-size: 0.75rem;
    }
    
    .management-controls {
        grid-template-columns: 1fr;
    }
    
    .study-controls {
        grid-template-columns: 1fr;
    }
    
    .answer-options {
        grid-template-columns: 1fr;
    }
}

/* Landscape mode adjustments */
@media (max-width: 812px) and (orientation: landscape) {
    .header {
        padding: 0.5rem 0;
    }
    
    .header h1 {
        font-size: 1.25rem;
    }
    
    .nav-tabs {
        padding: 0.25rem 0;
    }
    
    .nav-tab {
        padding: 0.5rem 1rem;
    }
    
    .module-content {
        padding: 0.75rem;
    }
}

/* Touch device optimizations */
@media (hover: none) and (pointer: coarse) {
    /* Larger touch targets */
    a, button, [role="button"], input[type="checkbox"], input[type="radio"] {
        min-height: 44px;
        min-width: 44px;
    }
    
    /* Remove hover effects on touch devices */
    .nav-tab:hover,
    .rob-btn:hover,
    button:hover {
        transform: none;
        box-shadow: none;
    }
    
    /* Add active states for better feedback */
    .nav-tab:active,
    .rob-btn:active,
    button:active {
        opacity: 0.8;
        transform: scale(0.98);
    }
}

/* Improved scrolling */
.scrollable-container {
    overflow-x: auto;
    -webkit-overflow-scrolling: touch;
    scroll-behavior: smooth;
    position: relative;
}

/* Hide scrollbars but keep functionality */
.scrollable-container::-webkit-scrollbar {
    height: 4px;
}

.scrollable-container::-webkit-scrollbar-track {
    background: var(--gray-100);
}

.scrollable-container::-webkit-scrollbar-thumb {
    background: var(--gray-400);
    border-radius: 2px;
}

/* Scroll indicators */
.table-responsive {
    position: relative;
}

.table-responsive::before,
.table-responsive::after {
    content: '';
    position: absolute;
    top: 0;
    bottom: 0;
    width: 20px;
    pointer-events: none;
    z-index: 10;
    opacity: 0;
    transition: opacity 0.3s ease;
}

.table-responsive::before {
    left: 0;
    background: linear-gradient(to right, rgba(255,255,255,0.9), transparent);
}

.table-responsive::after {
    right: 0;
    background: linear-gradient(to left, rgba(255,255,255,0.9), transparent);
}

.table-responsive.scrolled-left::before {
    opacity: 1;
}

.table-responsive.can-scroll-right::after {
    opacity: 1;
}

/* Touch active states */
.touch-active {
    transform: scale(0.95);
    opacity: 0.8;
}

/* Keyboard visible adjustments */
.keyboard-visible .header {
    position: static;
}

.keyboard-visible .nav-tabs {
    display: none;
}

/* Print styles for mobile */
@media print {
    .nav-tabs,
    .management-controls,
    .study-controls,
    button {
        display: none !important;
    }
    
    .study-item {
        page-break-inside: avoid;
    }
}
}
/* Authentication Styles */
.auth-modal {
    position: fixed !important;
    top: 0 !important;
    left: 0 !important;
    width: 100% !important;
    height: 100% !important;
    background: rgba(128, 128, 128, 0.4) !important;
    display: flex !important;
    align-items: center !important;
    justify-content: center !important;
    padding: 20px !important;
    z-index: 10000 !important;
    animation: fadeIn 0.2s ease;
    overflow-y: auto !important;
    box-sizing: border-box !important;
}

.auth-modal-content {
    background: white !important;
    width: 90% !important;
    max-width: 420px !important;
    border-radius: 16px !important;
    padding: 32px !important;
    position: relative !important;
    animation: modalFadeIn 0.3s ease !important;
    box-shadow: 0 20px 60px rgba(0, 0, 0, 0.3) !important;
    margin: auto !important;
}

/* Force center positioning for auth modals */
.auth-modal.center-modal {
    position: fixed !important;
    top: 0 !important;
    left: 0 !important;
    right: 0 !important;
    bottom: 0 !important;
    width: 100vw !important;
    height: 100vh !important;
    display: flex !important;
    align-items: center !important;
    justify-content: center !important;
    background: rgba(128, 128, 128, 0.4) !important;
    z-index: 999999 !important;
}

.auth-close-btn {
    position: absolute;
    top: 16px;
    right: 16px;
    background: none;
    border: none;
    font-size: 24px;
    color: var(--gray-400);
    cursor: pointer;
    transition: color 0.2s;
    padding: 8px;
}

.auth-close-btn:hover {
    color: var(--gray-600);
}

.auth-header {
    text-align: center;
    margin-bottom: 32px;
}

.auth-header h2 {
    font-size: 28px;
    font-weight: 700;
    color: var(--gray-900);
    margin-bottom: 8px;
}

.auth-header p {
    color: var(--gray-600);
    font-size: 14px;
}

.auth-form .form-group {
    margin-bottom: 20px;
}

.auth-form label {
    display: block;
    margin-bottom: 6px;
    font-size: 14px;
    font-weight: 500;
    color: var(--gray-700);
}

.auth-form input[type="text"],
.auth-form input[type="email"],
.auth-form input[type="password"] {
    width: 100%;
    padding: 12px 16px;
    border: 1px solid var(--gray-300);
    border-radius: 8px;
    font-size: 15px;
    transition: all 0.2s;
    background: white;
}

.auth-form input:focus {
    outline: none;
    border-color: var(--primary-500);
    box-shadow: 0 0 0 3px rgba(20, 184, 166, 0.1);
}

.form-options {
    display: flex;
    justify-content: space-between;
    align-items: center;
    margin-bottom: 24px;
    font-size: 14px;
}

.checkbox-label {
    display: flex;
    align-items: center;
    cursor: pointer;
}

.checkbox-label input[type="checkbox"] {
    margin-right: 8px;
}

.checkbox-label span {
    color: var(--gray-600);
}

.forgot-password {
    color: var(--primary-600);
    text-decoration: none;
    font-weight: 500;
}

.forgot-password:hover {
    color: var(--primary-700);
}

.auth-btn {
    width: 100%;
    padding: 12px 24px;
    border: none;
    border-radius: 8px;
    font-size: 16px;
    font-weight: 600;
    cursor: pointer;
    transition: all 0.2s;
    display: flex;
    align-items: center;
    justify-content: center;
    gap: 8px;
}

.auth-btn.primary {
    background: var(--primary-600);
    color: white;
}

.auth-btn.primary:hover {
    background: var(--primary-700);
    transform: translateY(-1px);
    box-shadow: 0 4px 12px rgba(20, 184, 166, 0.3);
}

.auth-btn.google {
    background: white;
    color: var(--gray-700);
    border: 1px solid var(--gray-300);
}

.auth-btn.google:hover {
    background: var(--gray-50);
    border-color: var(--gray-400);
}

.auth-divider {
    text-align: center;
    margin: 24px 0;
    position: relative;
}

.auth-divider span {
    background: white;
    padding: 0 16px;
    color: var(--gray-500);
    font-size: 14px;
    position: relative;
}

.auth-divider::before {
    content: "";
    position: absolute;
    top: 50%;
    left: 0;
    right: 0;
    height: 1px;
    background: var(--gray-300);
}

.auth-footer {
    text-align: center;
    margin-top: 24px;
    font-size: 14px;
    color: var(--gray-600);
}

.auth-footer a {
    color: var(--primary-600);
    text-decoration: none;
    font-weight: 500;
}

.auth-footer a:hover {
    color: var(--primary-700);
}

.auth-error,
.auth-success {
    padding: 12px 16px;
    border-radius: 8px;
    margin-top: 16px;
    font-size: 14px;
    text-align: center;
}

.auth-error {
    background: #fef2f2;
    color: #dc2626;
    border: 1px solid #fecaca;
}

.auth-success {
    background: #f0fdf4;
    color: #16a34a;
    border: 1px solid #bbf7d0;
}

/* User Menu Styles */
.user-menu {
    position: relative;
}

.user-menu-btn {
    display: flex;
    align-items: center;
    gap: 8px;
    padding: 8px 16px;
    background: white;
    border: 1px solid var(--gray-300);
    border-radius: 8px;
    cursor: pointer;
    font-size: 14px;
    font-weight: 500;
    color: var(--gray-700);
    transition: all 0.2s;
}

.user-menu-btn:hover {
    background: var(--gray-50);
    border-color: var(--gray-400);
}

.user-dropdown {
    position: absolute;
    top: calc(100% + 8px);
    right: 0;
    background: white;
    border: 1px solid var(--gray-200);
    border-radius: 8px;
    box-shadow: 0 10px 25px rgba(0, 0, 0, 0.1);
    min-width: 200px;
    z-index: 1000;
}

.user-dropdown a {
    display: flex;
    align-items: center;
    gap: 12px;
    padding: 12px 16px;
    color: var(--gray-700);
    text-decoration: none;
    font-size: 14px;
    transition: background 0.2s;
}

.user-dropdown a:hover {
    background: var(--gray-50);
}

.user-dropdown hr {
    margin: 4px 0;
    border: none;
    border-top: 1px solid var(--gray-200);
}

/* Login/Register Buttons in Header */
.login-btn,
.register-btn {
    padding: 8px 20px;
    border: none;
    border-radius: 8px;
    font-size: 14px;
    font-weight: 600;
    cursor: pointer;
    transition: all 0.2s;
    display: inline-flex;
    align-items: center;
    gap: 6px;
}

.login-btn {
    background: white;
    color: var(--primary-600);
    border: 1px solid var(--gray-300);
    margin-right: 8px;
    box-shadow: 0 1px 3px rgba(0, 0, 0, 0.1);
}

.login-btn:hover {
    background: var(--gray-50);
    border-color: var(--primary-600);
    box-shadow: 0 2px 8px rgba(0, 0, 0, 0.15);
}

.register-btn {
    background: white;
    color: var(--primary-600);
    border: 1px solid var(--gray-300);
    box-shadow: 0 1px 3px rgba(0, 0, 0, 0.1);
}

.register-btn:hover {
    background: var(--gray-50);
    border-color: var(--primary-600);
    box-shadow: 0 2px 8px rgba(0, 0, 0, 0.15);
}

/* Animations */
@keyframes fadeIn {
    from {
        opacity: 0;
    }
    to {
        opacity: 1;
    }
}

@keyframes slideUp {
    from {
        transform: translateY(20px) translateX(-50%);
        opacity: 0;
    }
    to {
        transform: translateY(0) translateX(-50%);
        opacity: 1;
    }
}

/* New centered modal animation */
@keyframes modalFadeIn {
    from {
        opacity: 0;
        transform: scale(0.9);
    }
    to {
        opacity: 1;
        transform: scale(1);
    }
}

/* 認證遮罩和模糊效果 */
.auth-overlay {
    position: fixed;
    top: 0;
    left: 0;
    width: 100%;
    height: 100%;
    background: rgba(0, 0, 0, 0.75);
    backdrop-filter: blur(8px);
    -webkit-backdrop-filter: blur(8px);
    display: flex;
    align-items: center;
    justify-content: center;
    z-index: 9999;
    animation: fadeIn 0.3s ease;
}

.auth-prompt {
    background: white;
    padding: 48px;
    border-radius: 20px;
    text-align: center;
    max-width: 450px;
    width: 90%;
    box-shadow: 0 25px 50px rgba(0, 0, 0, 0.3);
    animation: slideUp 0.4s ease;
}

.auth-prompt i.fas.fa-lock {
    font-size: 64px;
    color: var(--primary-600);
    margin-bottom: 24px;
}

.auth-prompt h2 {
    font-size: 28px;
    font-weight: 700;
    color: var(--gray-900);
    margin-bottom: 12px;
}

.auth-prompt p {
    font-size: 16px;
    color: var(--gray-600);
    margin-bottom: 32px;
}

.auth-prompt-buttons {
    display: flex;
    gap: 16px;
    justify-content: center;
    flex-wrap: wrap;
}

.auth-prompt-login,
.auth-prompt-register {
    padding: 14px 32px;
    border-radius: 10px;
    font-size: 16px;
    font-weight: 600;
    cursor: pointer;
    transition: all 0.3s;
    display: inline-flex;
    align-items: center;
    gap: 8px;
    border: none;
}

.auth-prompt-login {
    background: var(--primary-600);
    color: white;
}

.auth-prompt-login:hover {
    background: var(--primary-700);
    transform: translateY(-2px);
    box-shadow: 0 8px 20px rgba(20, 184, 166, 0.4);
}

.auth-prompt-register {
    background: white;
    color: var(--primary-600);
    border: 2px solid var(--primary-600);
}

.auth-prompt-register:hover {
    background: var(--primary-50);
    transform: translateY(-2px);
    box-shadow: 0 8px 20px rgba(20, 184, 166, 0.2);
}

/* 模糊效果類 */
.blur-content {
    filter: blur(5px);
    pointer-events: none;
    user-select: none;
    transition: filter 0.3s ease;
}

/* 防止滾動 */
body.auth-required {
    overflow: hidden;
}

/* 響應式設計 */
@media (max-width: 480px) {
    .auth-prompt {
        padding: 32px 24px;
    }

    .auth-prompt h2 {
        font-size: 24px;
    }

    .auth-prompt-buttons {
        flex-direction: column;
        width: 100%;
    }

    .auth-prompt-login,
    .auth-prompt-register {
        width: 100%;
        justify-content: center;
    }
}

/* 個人資料模態視窗樣式 */
.profile-modal {
    position: fixed;
    top: 0;
    left: 0;
    width: 100%;
    height: 100%;
    background: rgba(0, 0, 0, 0.6);
    display: flex;
    align-items: center;
    justify-content: center;
    z-index: 10000;
    animation: fadeIn 0.2s ease;
    overflow-y: auto;
    padding: 20px;
}

.profile-modal-content {
    background: white;
    width: 100%;
    max-width: 600px;
    border-radius: 16px;
    position: relative;
    animation: slideUp 0.3s ease;
    box-shadow: 0 20px 60px rgba(0, 0, 0, 0.3);
    max-height: 90vh;
    overflow-y: auto;
}

.profile-close-btn {
    position: absolute;
    top: 20px;
    right: 20px;
    background: none;
    border: none;
    font-size: 24px;
    color: var(--gray-400);
    cursor: pointer;
    transition: color 0.2s;
    padding: 8px;
    z-index: 1;
}

.profile-close-btn:hover {
    color: var(--gray-600);
}

.profile-header {
    text-align: center;
    padding: 40px 32px 32px;
    border-bottom: 1px solid var(--gray-200);
}

.profile-avatar {
    font-size: 64px;
    color: var(--primary-600);
    margin-bottom: 16px;
}

.profile-header h2 {
    font-size: 28px;
    font-weight: 700;
    color: var(--gray-900);
    margin-bottom: 8px;
}

.profile-header p {
    color: var(--gray-600);
    font-size: 14px;
}

.profile-form-container {
    padding: 32px;
}

.profile-form {
    display: flex;
    flex-direction: column;
    gap: 32px;
}

.profile-section {
    background: var(--gray-50);
    border-radius: 12px;
    padding: 24px;
    border-left: 4px solid var(--primary-500);
}

.profile-section h3 {
    display: flex;
    align-items: center;
    gap: 12px;
    font-size: 18px;
    font-weight: 600;
    color: var(--gray-900);
    margin-bottom: 16px;
}

.profile-section h3 i {
    color: var(--primary-600);
}

.section-description {
    color: var(--gray-600);
    font-size: 14px;
    margin-bottom: 16px;
    font-style: italic;
}

.form-group {
    margin-bottom: 20px;
    position: relative;
}

.form-group label {
    display: block;
    margin-bottom: 6px;
    font-size: 14px;
    font-weight: 500;
    color: var(--gray-700);
}

.form-group input[type="text"],
.form-group input[type="email"],
.form-group input[type="password"] {
    width: 100%;
    padding: 12px 16px;
    border: 2px solid var(--gray-300);
    border-radius: 8px;
    font-size: 15px;
    transition: all 0.2s;
    background: white;
}

.form-group input:focus {
    outline: none;
    border-color: var(--primary-500);
    box-shadow: 0 0 0 3px rgba(20, 184, 166, 0.1);
}

.form-group input.readonly-input {
    background: var(--gray-100);
    color: var(--gray-600);
    cursor: not-allowed;
}

.form-group input.field-valid {
    border-color: var(--success);
    background-color: rgba(16, 185, 129, 0.05);
}

.form-group input.field-invalid {
    border-color: var(--error);
    background-color: rgba(239, 68, 68, 0.05);
}

.field-error {
    color: var(--error);
    font-size: 12px;
    margin-top: 4px;
    display: flex;
    align-items: center;
    gap: 4px;
}

.field-error::before {
    content: "⚠";
    font-size: 14px;
}

.password-input-wrapper {
    position: relative;
}

.password-toggle {
    position: absolute;
    right: 12px;
    top: 50%;
    transform: translateY(-50%);
    background: none;
    border: none;
    color: var(--gray-400);
    cursor: pointer;
    font-size: 16px;
    transition: color 0.2s;
    padding: 4px;
}

.password-toggle:hover {
    color: var(--gray-600);
}

.password-strength {
    margin-top: 8px;
}

.strength-bar {
    height: 4px;
    background: var(--gray-200);
    border-radius: 2px;
    overflow: hidden;
    margin-bottom: 4px;
}

.strength-fill {
    height: 100%;
    transition: all 0.3s ease;
    width: 0%;
}

.strength-text {
    font-size: 12px;
    font-weight: 500;
}

.profile-actions {
    display: flex;
    gap: 16px;
    justify-content: flex-end;
    padding-top: 24px;
    border-top: 1px solid var(--gray-200);
}

.btn-primary,
.btn-secondary {
    padding: 12px 24px;
    border-radius: 8px;
    font-size: 16px;
    font-weight: 600;
    cursor: pointer;
    transition: all 0.2s;
    display: inline-flex;
    align-items: center;
    gap: 8px;
    border: none;
}

.btn-primary {
    background: var(--primary-600);
    color: white;
}

.btn-primary:hover {
    background: var(--primary-700);
    transform: translateY(-1px);
    box-shadow: 0 4px 12px rgba(20, 184, 166, 0.3);
}

.btn-secondary {
    background: var(--gray-100);
    color: var(--gray-700);
    border: 1px solid var(--gray-300);
}

.btn-secondary:hover {
    background: var(--gray-200);
    border-color: var(--gray-400);
}

.profile-message {
    margin: 20px 32px;
    padding: 12px 16px;
    border-radius: 8px;
    font-size: 14px;
    display: flex;
    align-items: center;
    gap: 8px;
}

.profile-message.info {
    background: var(--accent-50);
    color: var(--accent-700);
    border: 1px solid var(--accent-200);
}

.profile-message.success {
    background: #f0fdf4;
    color: #16a34a;
    border: 1px solid #bbf7d0;
}

.profile-message.error {
    background: #fef2f2;
    color: #dc2626;
    border: 1px solid #fecaca;
}

.profile-message.info::before {
    content: "ℹ";
    font-weight: bold;
}

.profile-message.success::before {
    content: "✓";
    font-weight: bold;
}

.profile-message.error::before {
    content: "⚠";
    font-weight: bold;
}

/* 響應式設計 */
@media (max-width: 768px) {
    .profile-modal {
        padding: 10px;
    }

    .profile-modal-content {
        max-height: 95vh;
    }

    .profile-header {
        padding: 32px 24px 24px;
    }

    .profile-form-container {
        padding: 24px;
    }

    .profile-section {
        padding: 20px;
    }

    .profile-actions {
        flex-direction: column;
    }

    .btn-primary,
    .btn-secondary {
        width: 100%;
        justify-content: center;
    }
}

@media (max-width: 480px) {
    .profile-header h2 {
        font-size: 24px;
    }

    .profile-avatar {
        font-size: 48px;
    }

    .profile-section h3 {
        font-size: 16px;
    }
}

/* 註冊表單額外樣式 */
.field-hint {
    font-size: 12px;
    color: var(--gray-500);
    margin-top: 4px;
    display: block;
}

.form-group label {
    display: flex;
    align-items: center;
    gap: 4px;
}

.form-group label::after {
    content: "";
}

.form-group label:has-text("*")::after {
    content: "*";
    color: var(--error);
    font-weight: bold;
}

.required-field {
    color: var(--error);
    font-size: 12px;
}

/* Tab Access Control Styles */
.tab-btn.restricted-tab {
    opacity: 0.6;
    position: relative;
}

.tab-btn.restricted-tab:hover {
    opacity: 0.8;
    cursor: pointer;
}

.tab-btn.restricted-tab .lock-icon {
    color: #f59e0b;
    margin-left: 5px;
    font-size: 0.8em;
}

.tab-btn.restricted-tab:hover .lock-icon {
    animation: shake 0.5s ease-in-out;
}

@keyframes shake {
    0%, 100% { transform: translateX(0); }
    25% { transform: translateX(-2px); }
    75% { transform: translateX(2px); }
}

/* Auth buttons in access denied modal */
.auth-buttons {
    display: flex;
    gap: 12px;
    flex-wrap: wrap;
    justify-content: center;
    margin-top: 20px;
}

.auth-buttons .auth-btn {
    flex: 1;
    min-width: 120px;
}

.auth-buttons .auth-btn.secondary {
    background: #6b7280;
    color: white;
}

.auth-buttons .auth-btn.secondary:hover {
    background: #4b5563;
}

/* User Controls Layout */
.user-controls {
    display: flex;
    align-items: center;
    gap: 12px;
}

/* Direct Logout Button */
.logout-btn-direct {
    display: flex;
    align-items: center;
    gap: 6px;
    padding: 8px 16px;
    background: #dc2626;
    color: white;
    border: none;
    border-radius: 6px;
    font-size: 14px;
    font-weight: 500;
    cursor: pointer;
    transition: background 0.2s ease;
}

.logout-btn-direct:hover {
    background: #b91c1c;
}

.logout-btn-direct i {
    font-size: 13px;
}

/* Responsive layout for smaller screens */
@media (max-width: 768px) {
    .user-controls {
        flex-direction: column;
        gap: 8px;
    }

    .logout-btn-direct span {
        display: none;
    }

    .logout-btn-direct {
        padding: 8px;
        min-width: auto;
    }

    .auth-modal {
        padding: 15px;
    }

    .auth-modal-content {
        width: 95%;
        padding: 24px;
    }
}

/* ========================================
   Effect Size Interpretation Guide Styles
   ======================================== */

.effect-size-guide {
    background: white;
    border-radius: var(--radius-lg);
    padding: var(--space-6);
    margin-bottom: var(--space-6);
    box-shadow: var(--shadow-md);
}

.effect-size-guide h3 {
    display: flex;
    align-items: center;
    gap: 10px;
    color: var(--gray-800);
    margin-bottom: var(--space-4);
    font-size: 1.25rem;
}

.effect-size-guide h3 i {
    color: var(--primary-500);
}

.guide-intro {
    color: var(--gray-600);
    margin-bottom: var(--space-6);
    line-height: 1.6;
}

.effect-size-cards {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));
    gap: var(--space-4);
    margin-bottom: var(--space-6);
}

.es-card {
    border-radius: var(--radius);
    overflow: hidden;
    box-shadow: var(--shadow);
    transition: transform 0.2s ease, box-shadow 0.2s ease;
}

.es-card:hover {
    transform: translateY(-2px);
    box-shadow: var(--shadow-lg);
}

.es-card-header {
    padding: var(--space-3) var(--space-4);
    display: flex;
    align-items: center;
    gap: 10px;
    color: white;
}

.es-card-header h4 {
    margin: 0;
    font-size: 0.95rem;
    font-weight: 600;
}

.es-card-header i {
    font-size: 1.1rem;
}

.smd-header {
    background: linear-gradient(135deg, var(--primary-500) 0%, var(--primary-600) 100%);
}

.or-header {
    background: linear-gradient(135deg, var(--accent-500) 0%, var(--accent-600) 100%);
}

.rr-header {
    background: linear-gradient(135deg, #8b5cf6 0%, #7c3aed 100%);
}

.corr-header {
    background: linear-gradient(135deg, #ec4899 0%, #db2777 100%);
}

.es-card-body {
    padding: var(--space-4);
    background: var(--gray-50);
}

.es-scale {
    display: flex;
    flex-direction: column;
    gap: var(--space-3);
}

.es-level {
    display: flex;
    align-items: center;
    gap: var(--space-3);
    padding: var(--space-2) var(--space-3);
    border-radius: var(--radius-sm);
    background: white;
}

.es-level.small {
    border-left: 4px solid #10b981;
}

.es-level.medium {
    border-left: 4px solid #f59e0b;
}

.es-level.large {
    border-left: 4px solid #ef4444;
}

.es-value {
    font-family: var(--font-mono);
    font-weight: 600;
    font-size: 0.9rem;
    color: var(--gray-800);
    min-width: 70px;
}

.es-label {
    font-weight: 600;
    font-size: 0.85rem;
    color: var(--gray-700);
    min-width: 60px;
}

.es-desc {
    font-size: 0.8rem;
    color: var(--gray-500);
}

.es-note {
    margin-top: var(--space-3);
    font-size: 0.8rem;
    color: var(--gray-500);
    display: flex;
    align-items: center;
    gap: 6px;
}

.es-note i {
    color: var(--info);
}

.interpretation-tips {
    background: linear-gradient(135deg, var(--warning) 0%, #d97706 100%);
    color: white;
    padding: var(--space-4);
    border-radius: var(--radius);
}

.interpretation-tips h4 {
    display: flex;
    align-items: center;
    gap: 8px;
    margin-bottom: var(--space-3);
    font-size: 1rem;
}

.interpretation-tips ul {
    margin: 0;
    padding-left: var(--space-5);
}

.interpretation-tips li {
    margin-bottom: var(--space-2);
    line-height: 1.5;
}

.interpretation-tips strong {
    color: #fef3c7;
}

/* Responsive adjustments */
@media (max-width: 768px) {
    .effect-size-cards {
        grid-template-columns: 1fr;
    }

    .es-level {
        flex-wrap: wrap;
    }

    .es-desc {
        width: 100%;
        margin-top: 4px;
    }
}

/* ========================================
   Forest Plot Guide Styles
   ======================================== */

.forest-plot-guide {
    display: flex;
    flex-direction: column;
    gap: var(--space-6);
}

.forest-intro {
    background: var(--gray-50);
    padding: var(--space-4);
    border-radius: var(--radius);
    border-left: 4px solid var(--primary-500);
}

.forest-intro p {
    margin: 0;
    color: var(--gray-700);
    line-height: 1.6;
}

.forest-elements h4,
.interpretation-steps h4,
.interpretation-scenarios h4,
.forest-warnings h4 {
    display: flex;
    align-items: center;
    gap: 10px;
    color: var(--gray-800);
    margin-bottom: var(--space-4);
}

.forest-elements h4 i,
.interpretation-steps h4 i,
.interpretation-scenarios h4 i,
.forest-warnings h4 i {
    color: var(--primary-500);
}

.elements-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(220px, 1fr));
    gap: var(--space-4);
}

.element-card {
    background: white;
    border-radius: var(--radius);
    padding: var(--space-4);
    box-shadow: var(--shadow);
    display: flex;
    gap: var(--space-3);
    transition: transform 0.2s ease;
}

.element-card:hover {
    transform: translateY(-2px);
}

.element-icon {
    width: 50px;
    height: 50px;
    background: linear-gradient(135deg, var(--primary-100) 0%, var(--primary-200) 100%);
    border-radius: var(--radius);
    display: flex;
    align-items: center;
    justify-content: center;
    flex-shrink: 0;
}

.element-icon i {
    font-size: 1.25rem;
    color: var(--primary-600);
}

.element-content h5 {
    margin: 0 0 6px 0;
    color: var(--gray-800);
    font-size: 0.95rem;
}

.element-content p {
    margin: 0;
    color: var(--gray-600);
    font-size: 0.85rem;
    line-height: 1.4;
}

.element-note {
    margin-top: 6px !important;
    color: var(--primary-600) !important;
    font-size: 0.8rem !important;
}

/* Interpretation Steps */
.steps-container {
    display: flex;
    flex-direction: column;
    gap: var(--space-3);
}

.step-item {
    display: flex;
    gap: var(--space-4);
    background: white;
    padding: var(--space-4);
    border-radius: var(--radius);
    box-shadow: var(--shadow);
}

.step-number {
    width: 40px;
    height: 40px;
    background: linear-gradient(135deg, var(--primary-500) 0%, var(--primary-600) 100%);
    color: white;
    border-radius: 50%;
    display: flex;
    align-items: center;
    justify-content: center;
    font-weight: 700;
    font-size: 1.1rem;
    flex-shrink: 0;
}

.step-content h5 {
    margin: 0 0 8px 0;
    color: var(--gray-800);
}

.step-content ul {
    margin: 0;
    padding-left: var(--space-5);
    color: var(--gray-600);
}

.step-content li {
    margin-bottom: 4px;
    font-size: 0.9rem;
}

/* Interpretation Scenarios */
.scenarios-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(260px, 1fr));
    gap: var(--space-4);
}

.scenario-box {
    border-radius: var(--radius);
    padding: var(--space-4);
    box-shadow: var(--shadow);
}

.scenario-box.favorable {
    background: linear-gradient(135deg, #ecfdf5 0%, #d1fae5 100%);
    border: 1px solid #a7f3d0;
}

.scenario-box.mixed {
    background: linear-gradient(135deg, #fffbeb 0%, #fef3c7 100%);
    border: 1px solid #fde68a;
}

.scenario-box.problematic {
    background: linear-gradient(135deg, #fef2f2 0%, #fee2e2 100%);
    border: 1px solid #fecaca;
}

.scenario-header {
    display: flex;
    align-items: center;
    gap: 8px;
    margin-bottom: var(--space-3);
}

.scenario-header h5 {
    margin: 0;
    font-size: 1rem;
}

.scenario-box.favorable .scenario-header i { color: #059669; }
.scenario-box.mixed .scenario-header i { color: #d97706; }
.scenario-box.problematic .scenario-header i { color: #dc2626; }

.scenario-box ul {
    margin: 0;
    padding-left: var(--space-5);
    font-size: 0.9rem;
    color: var(--gray-700);
}

.scenario-box li {
    margin-bottom: 4px;
}

.scenario-result {
    margin-top: var(--space-3);
    font-weight: 600;
    font-size: 0.9rem;
}

.scenario-box.favorable .scenario-result { color: #059669; }
.scenario-box.mixed .scenario-result { color: #d97706; }
.scenario-box.problematic .scenario-result { color: #dc2626; }

/* Forest Warnings */
.forest-warnings {
    background: linear-gradient(135deg, var(--info) 0%, var(--accent-600) 100%);
    padding: var(--space-4);
    border-radius: var(--radius);
    color: white;
}

.forest-warnings h4 {
    color: white;
    margin-bottom: var(--space-4);
}

.forest-warnings h4 i {
    color: #fef3c7;
}

.warnings-list {
    display: flex;
    flex-direction: column;
    gap: var(--space-3);
}

.warning-item {
    display: flex;
    align-items: flex-start;
    gap: 10px;
}

.warning-item i {
    color: #a5f3fc;
    margin-top: 2px;
}

.warning-item p {
    margin: 0;
    font-size: 0.9rem;
    line-height: 1.5;
}

.warning-item strong {
    color: #fef3c7;
}

/* Responsive */
@media (max-width: 768px) {
    .elements-grid {
        grid-template-columns: 1fr;
    }

    .scenarios-grid {
        grid-template-columns: 1fr;
    }

    .step-item {
        flex-direction: column;
        align-items: flex-start;
    }
}

/* ========================================
   Heterogeneity Decision Tree Styles
   ======================================== */

.section-intro {
    color: var(--gray-600);
    margin-bottom: var(--space-6);
    line-height: 1.6;
}

.heterogeneity-decision-tree {
    display: flex;
    flex-direction: column;
    align-items: center;
    gap: var(--space-4);
}

.decision-level {
    width: 100%;
    display: flex;
    justify-content: center;
}

.decision-start {
    background: linear-gradient(135deg, #ef4444 0%, #dc2626 100%);
    color: white;
    padding: var(--space-4) var(--space-6);
    border-radius: var(--radius);
    text-align: center;
    box-shadow: var(--shadow-md);
}

.decision-start i {
    font-size: 1.5rem;
    margin-bottom: 8px;
    display: block;
}

.decision-start h4 {
    margin: 0;
    font-size: 1.1rem;
}

.decision-arrow-down {
    color: var(--gray-400);
    font-size: 1.5rem;
}

.decision-question {
    background: var(--gray-100);
    padding: var(--space-3) var(--space-6);
    border-radius: var(--radius);
    border: 2px solid var(--gray-300);
}

.decision-question h5 {
    margin: 0;
    color: var(--gray-700);
    font-size: 1rem;
}

.decision-branches {
    display: grid;
    grid-template-columns: 1fr 1fr;
    gap: var(--space-4);
    width: 100%;
    max-width: 800px;
}

.decision-branch {
    background: white;
    border-radius: var(--radius);
    overflow: hidden;
    box-shadow: var(--shadow);
}

.branch-header {
    padding: var(--space-3);
    font-weight: 600;
    text-align: center;
}

.branch-header.yes {
    background: linear-gradient(135deg, #10b981 0%, #059669 100%);
    color: white;
}

.branch-header.no {
    background: linear-gradient(135deg, #f59e0b 0%, #d97706 100%);
    color: white;
}

.branch-content {
    padding: var(--space-4);
}

.branch-content p {
    margin: 0 0 var(--space-3) 0;
    color: var(--gray-600);
    font-size: 0.9rem;
}

.branch-action {
    display: flex;
    align-items: center;
    gap: 8px;
    padding: var(--space-2) var(--space-3);
    background: var(--primary-50);
    border-radius: var(--radius-sm);
    color: var(--primary-700);
    font-size: 0.85rem;
}

.branch-action.warning {
    background: #fef3c7;
    color: #92400e;
}

.source-exploration {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(240px, 1fr));
    gap: var(--space-4);
    width: 100%;
}

.source-category {
    background: white;
    border-radius: var(--radius);
    overflow: hidden;
    box-shadow: var(--shadow);
}

.source-header {
    padding: var(--space-3);
    display: flex;
    align-items: center;
    gap: 10px;
    color: white;
}

.source-header h6 {
    margin: 0;
    font-size: 0.95rem;
}

.source-header.clinical {
    background: linear-gradient(135deg, var(--primary-500) 0%, var(--primary-600) 100%);
}

.source-header.methodological {
    background: linear-gradient(135deg, var(--accent-500) 0%, var(--accent-600) 100%);
}

.source-header.statistical {
    background: linear-gradient(135deg, #8b5cf6 0%, #7c3aed 100%);
}

.source-category ul {
    padding: var(--space-3) var(--space-4);
    margin: 0;
    list-style: none;
}

.source-category li {
    padding: var(--space-2) 0;
    border-bottom: 1px solid var(--gray-100);
    font-size: 0.85rem;
    color: var(--gray-600);
}

.source-category li:last-child {
    border-bottom: none;
}

.strategy-options {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(200px, 1fr));
    gap: var(--space-4);
    width: 100%;
}

.strategy-card {
    background: white;
    border-radius: var(--radius);
    padding: var(--space-4);
    text-align: center;
    box-shadow: var(--shadow);
    transition: transform 0.2s ease;
}

.strategy-card:hover {
    transform: translateY(-3px);
}

.strategy-icon {
    width: 50px;
    height: 50px;
    background: linear-gradient(135deg, var(--primary-100) 0%, var(--primary-200) 100%);
    border-radius: 50%;
    display: flex;
    align-items: center;
    justify-content: center;
    margin: 0 auto var(--space-3) auto;
}

.strategy-icon i {
    font-size: 1.25rem;
    color: var(--primary-600);
}

.strategy-card h6 {
    margin: 0 0 8px 0;
    color: var(--gray-800);
    font-size: 1rem;
}

.strategy-card p {
    margin: 0 0 var(--space-3) 0;
    color: var(--gray-500);
    font-size: 0.85rem;
}

.strategy-when {
    background: var(--gray-50);
    padding: var(--space-2);
    border-radius: var(--radius-sm);
    font-size: 0.8rem;
    color: var(--gray-600);
}

.heterogeneity-reminder {
    background: linear-gradient(135deg, var(--info) 0%, var(--accent-600) 100%);
    color: white;
    padding: var(--space-4);
    border-radius: var(--radius);
    display: flex;
    gap: var(--space-4);
    width: 100%;
    max-width: 800px;
}

.heterogeneity-reminder > i {
    font-size: 2rem;
    color: #fef3c7;
    flex-shrink: 0;
}

.reminder-content h6 {
    margin: 0 0 8px 0;
    color: #fef3c7;
    font-size: 1rem;
}

.reminder-content p {
    margin: 0;
    font-size: 0.9rem;
    line-height: 1.6;
}

/* Heterogeneity Decision Tree Responsive */
@media (max-width: 768px) {
    .decision-branches {
        grid-template-columns: 1fr;
    }

    .source-exploration {
        grid-template-columns: 1fr;
    }

    .strategy-options {
        grid-template-columns: repeat(2, 1fr);
    }

    .heterogeneity-reminder {
        flex-direction: column;
        text-align: center;
    }
}

@media (max-width: 480px) {
    .strategy-options {
        grid-template-columns: 1fr;
    }
}

/* ========================================
   PRISMA 2020 Flow Chart Styles
   ======================================== */

.prisma-guide {
    display: flex;
    flex-direction: column;
    gap: var(--space-6);
}

.prisma-intro {
    background: var(--gray-50);
    padding: var(--space-4);
    border-radius: var(--radius);
    border-left: 4px solid var(--primary-500);
}

.prisma-intro p {
    margin: 0;
    color: var(--gray-700);
    line-height: 1.6;
}

.prisma-flowchart h4,
.prisma-updates h4,
.prisma-tips h4,
.prisma-resources h4 {
    display: flex;
    align-items: center;
    gap: 10px;
    margin-bottom: var(--space-4);
    color: var(--gray-800);
}

.prisma-flowchart h4 i,
.prisma-updates h4 i,
.prisma-tips h4 i,
.prisma-resources h4 i {
    color: var(--primary-500);
}

/* PRISMA Stages */
.prisma-stage {
    background: white;
    border-radius: var(--radius);
    overflow: hidden;
    box-shadow: var(--shadow);
    margin-bottom: var(--space-4);
}

.stage-header {
    display: flex;
    align-items: center;
    gap: var(--space-3);
    padding: var(--space-3) var(--space-4);
    color: white;
}

.prisma-stage.identification .stage-header {
    background: linear-gradient(135deg, #3b82f6 0%, #2563eb 100%);
}

.prisma-stage.screening .stage-header {
    background: linear-gradient(135deg, #8b5cf6 0%, #7c3aed 100%);
}

.prisma-stage.included .stage-header {
    background: linear-gradient(135deg, #10b981 0%, #059669 100%);
}

.stage-number {
    width: 32px;
    height: 32px;
    background: rgba(255, 255, 255, 0.2);
    border-radius: 50%;
    display: flex;
    align-items: center;
    justify-content: center;
    font-weight: 700;
    font-size: 1rem;
}

.stage-header h5 {
    margin: 0;
    font-size: 1rem;
}

.stage-content {
    padding: var(--space-4);
}

.stage-boxes {
    display: grid;
    grid-template-columns: 1fr 1fr;
    gap: var(--space-4);
    margin-bottom: var(--space-4);
}

.stage-box {
    background: var(--gray-50);
    padding: var(--space-3);
    border-radius: var(--radius-sm);
}

.stage-box h6 {
    margin: 0 0 8px 0;
    color: var(--gray-800);
    font-size: 0.9rem;
}

.stage-box ul {
    margin: 0;
    padding-left: var(--space-4);
    font-size: 0.85rem;
    color: var(--gray-600);
}

.stage-box li {
    margin-bottom: 4px;
}

.stage-action {
    display: flex;
    align-items: center;
    justify-content: center;
    gap: 10px;
    padding: var(--space-2);
    background: var(--primary-50);
    border-radius: var(--radius-sm);
    color: var(--primary-700);
    font-size: 0.9rem;
}

/* Screening Steps */
.screening-steps {
    display: flex;
    flex-direction: column;
    gap: var(--space-3);
}

.screening-step {
    display: flex;
    align-items: center;
    gap: var(--space-4);
    padding: var(--space-3);
    background: var(--gray-50);
    border-radius: var(--radius-sm);
}

.step-main {
    flex: 1;
}

.step-main strong {
    display: block;
    margin-bottom: 4px;
    color: var(--gray-800);
}

.step-main p {
    margin: 0;
    font-size: 0.85rem;
    color: var(--gray-600);
}

.step-excluded {
    display: flex;
    align-items: center;
    gap: 6px;
    padding: var(--space-2) var(--space-3);
    background: #fef2f2;
    border-radius: var(--radius-sm);
    color: #dc2626;
    font-size: 0.8rem;
}

/* Included Details */
.included-details {
    display: flex;
    flex-direction: column;
    align-items: center;
    gap: var(--space-3);
}

.included-box {
    width: 100%;
    padding: var(--space-3);
    background: var(--gray-50);
    border-radius: var(--radius-sm);
    text-align: center;
}

.included-box.highlight {
    background: linear-gradient(135deg, var(--primary-50) 0%, var(--primary-100) 100%);
    border: 2px solid var(--primary-300);
}

.included-box h6 {
    margin: 0 0 4px 0;
    color: var(--gray-800);
}

.included-box p {
    margin: 0;
    font-size: 0.85rem;
    color: var(--gray-600);
}

.included-arrow {
    color: var(--gray-400);
    font-size: 1.25rem;
}

/* PRISMA Updates */
.updates-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));
    gap: var(--space-4);
}

.update-item {
    display: flex;
    gap: var(--space-3);
    padding: var(--space-3);
    background: white;
    border-radius: var(--radius);
    box-shadow: var(--shadow);
}

.update-item > i {
    color: var(--success);
    font-size: 1.25rem;
    flex-shrink: 0;
}

.update-item strong {
    display: block;
    margin-bottom: 4px;
    color: var(--gray-800);
}

.update-item p {
    margin: 0;
    font-size: 0.85rem;
    color: var(--gray-600);
}

/* PRISMA Tips */
.prisma-tips {
    background: linear-gradient(135deg, var(--info) 0%, var(--accent-600) 100%);
    padding: var(--space-4);
    border-radius: var(--radius);
    color: white;
}

.prisma-tips h4 {
    color: white;
    margin-bottom: var(--space-3);
}

.prisma-tips h4 i {
    color: #fef3c7;
}

.prisma-tips ul {
    margin: 0;
    padding-left: var(--space-5);
}

.prisma-tips li {
    margin-bottom: 8px;
    line-height: 1.5;
}

.prisma-tips strong {
    color: #fef3c7;
}

/* PRISMA Resources */
.prisma-resources {
    background: var(--gray-50);
    padding: var(--space-4);
    border-radius: var(--radius);
}

.resource-links {
    display: flex;
    flex-wrap: wrap;
    gap: var(--space-3);
}

.resource-link {
    display: flex;
    align-items: center;
    gap: 8px;
    padding: var(--space-2) var(--space-4);
    background: white;
    border: 1px solid var(--gray-200);
    border-radius: var(--radius);
    color: var(--primary-600);
    text-decoration: none;
    font-size: 0.9rem;
    transition: all 0.2s ease;
}

.resource-link:hover {
    background: var(--primary-50);
    border-color: var(--primary-300);
    transform: translateY(-2px);
}

.resource-link i {
    color: var(--primary-500);
}

/* PRISMA Responsive */
@media (max-width: 768px) {
    .stage-boxes {
        grid-template-columns: 1fr;
    }

    .screening-step {
        flex-direction: column;
        align-items: flex-start;
    }

    .step-excluded {
        align-self: flex-end;
    }

    .updates-grid {
        grid-template-columns: 1fr;
    }

    .resource-links {
        flex-direction: column;
    }
}